E
Elizabeth G. Loboa
Researcher at University of Missouri
Publications - 86
Citations - 4494
Elizabeth G. Loboa is an academic researcher from University of Missouri. The author has contributed to research in topics: Tissue engineering & Mesenchymal stem cell. The author has an hindex of 40, co-authored 86 publications receiving 4039 citations. Previous affiliations of Elizabeth G. Loboa include Stanford University & Southern Methodist University.
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Cytoskeletal and focal adhesion influences on mesenchymal stem cell shape, mechanical properties, and differentiation down osteogenic, adipogenic, and chondrogenic pathways.
TL;DR: This review analyzes the significant contribution of actin and integrin distribution, and the smaller role of microtubules, in regulating MSC fate and shows that mechanical stimuli can control MSC lineage specification.
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Osteogenic Differentiation of Human Mesenchymal Stem Cells in Collagen Matrices: Effect of Uniaxial Cyclic Tensile Strain on Bone Morphogenetic Protein (BMP-2) mRNA Expression
TL;DR: This is the first report of the culture of bone marrow-derived hMSCs in 3D collagen matrices under cyclic strain, and the first demonstration that strain alone can induce osteogenic differentiation without the addition of osteogenic supplements.
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Comparative review of growth factors for induction of three-dimensional in vitro chondrogenesis in human mesenchymal stem cells isolated from bone marrow and adipose tissue.
TL;DR: A thorough review of the literature indicates that human MSCs (hMSCs) appear to exhibit the highest chondrogenic potential in three-dimensional culture in the medium containing both dexamethasone and TGFbeta-3.
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Naturally derived and synthetic scaffolds for skeletal muscle reconstruction.
Matthew T. Wolf,Christopher L. Dearth,Sonya B. Sonnenberg,Elizabeth G. Loboa,Stephen F. Badylak +4 more
TL;DR: Advances in scaffolds using muscle tissue engineering are reviewed and next generation naturally derived/synthetic "hybrid materials" would combine the advantageous properties of these materials to create an optimal platform for cell/drug delivery and possess inherent bioactive properties.
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Effects of serial passaging on the adipogenic and osteogenic differentiation potential of adipose-derived human mesenchymal stem cells.
TL;DR: The results of this study indicate that adipose-derived hMSCs are capable of both adipogenic and osteogenic differentiation through 10 passages (34 population doublings) but that osteogenic differentiate may start to dominate at later passages.