E
Elizabeth S. Fernandes
Researcher at King's College London
Publications - 97
Citations - 4282
Elizabeth S. Fernandes is an academic researcher from King's College London. The author has contributed to research in topics: Receptor & Kinin. The author has an hindex of 32, co-authored 87 publications receiving 3634 citations. Previous affiliations of Elizabeth S. Fernandes include Universidade Federal de Santa Catarina & Federal University of Maranhão.
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Anti-inflammatory effects of compounds alpha-humulene and (−)-trans-caryophyllene isolated from the essential oil of Cordia verbenacea
Elizabeth S. Fernandes,Giselle F. Passos,Rodrigo Medeiros,Fernanda Marques da Cunha,Juliano Ferreira,Maria M. Campos,Luiz Francisco Pianowski,João B. Calixto +7 more
TL;DR: Findings indicate that alpha-humulene and (-)-trans-caryophyllene, derived from the essential oil of C. verbenacea, might represent important tools for the management and/or treatment of inflammatory diseases.
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The functions of TRPA1 and TRPV1: moving away from sensory nerves
TL;DR: The expression, functionality and roles of these non‐neuronal TRP channels away from sensory nerves are discussed to demonstrate the diverse nature of TRPV1 and TRPA1 in addition to a direct role in pain and neurogenic inflammation.
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Kinin B1 receptors: key G-protein-coupled receptors and their role in inflammatory and painful processes
João B. Calixto,Rodrigo Medeiros,Elizabeth S. Fernandes,Juliano Ferreira,Daniela Almeida Cabrini,Maria M. Campos +5 more
TL;DR: The main advances achieved in the last 5 years about the participation of kinin B1 receptors in painful and inflammatory disorders are remarked and some groups of chronic diseases are pointed out, in which the strategic development of nonpeptidic oral‐available and selective B1 receptor antagonists could have a potential relevant therapeutic interest.
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Anti-inflammatory and anti-allergic properties of the essential oil and active compounds from Cordia verbenacea
Giselle F. Passos,Elizabeth S. Fernandes,Fernanda Marques da Cunha,Juliano Ferreira,Luiz Francisco Pianowski,Maria M. Campos,João B. Calixto +6 more
TL;DR: Cordia verbenacea essential oil or its constituents might represent new therapeutic options for the treatment of inflammatory diseases and some active compounds, probably by interfering with TNFalpha production, showed marked anti-inflammatory effects.
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Involvement of monoaminergic system in the antidepressant-like effect of the hydroalcoholic extract of Siphocampylus verticillatus.
Ana Lúcia S. Rodrigues,Gisele L. da Silva,Andreza S. Mateussi,Elizabeth S. Fernandes,Obdulio Gomes Miguel,Rosendo A. Yunes,João B. Calixto,Adair R.S. Santos +7 more
TL;DR: The biochemical data show that the extract of S. verticillatus elicited a significant antidepressant-like effect, when assessed in the TST and FST in mice, which seems to involve an interaction with adrenergic, dopaminergic, glutamatergic and serotonergic systems.