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Elzbieta Brzuszkiewicz
Researcher at University of Göttingen
Publications - 35
Citations - 3629
Elzbieta Brzuszkiewicz is an academic researcher from University of Göttingen. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 24, co-authored 35 publications receiving 3034 citations. Previous affiliations of Elzbieta Brzuszkiewicz include Academy of Sciences Leopoldina.
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Journal ArticleDOI
Escherichia coli Induces DNA Double-Strand Breaks in Eukaryotic Cells
Jean-Philippe Nougayrède,Stefan Homburg,Frédéric Taieb,Michèle Boury,Elzbieta Brzuszkiewicz,Gerhard Gottschalk,Carmen Buchrieser,Jörg Hacker,Ulrich Dobrindt,Eric Oswald +9 more
TL;DR: Discovery of hybrid peptide-polyketide genotoxins in E. coli will change the view on pathogenesis and commensalism and open new biotechnological applications.
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Comparative genome and phenotypic analysis of three Clostridioides difficile strains isolated from a single patient provide insight into multiple infection of C. difficile.
Uwe Groß,Elzbieta Brzuszkiewicz,Katrin Gunka,Jessica Starke,Thomas Riedel,Boyke Bunk,Cathrin Spröer,Daniela Wetzel,Anja Poehlein,Cynthia Maria Chibani,Wolfgang Bohne,Jörg Overmann,Ortrud Zimmermann,Rolf Daniel,Heiko Liesegang +14 more
TL;DR: Findings show that evolutionary events based on horizontal gene transfer occur within an ongoing CDI and contribute to the adaptation of the species by the introduction of new genes into the genomes.
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How to become a uropathogen: Comparative genomic analysis of extraintestinal pathogenic Escherichia coli strains
Elzbieta Brzuszkiewicz,Holger Brüggemann,Heiko Liesegang,Melanie Emmerth,Tobias Ölschläger,Gábor Nagy,Kaj Albermann,Christian Wagner,Carmen Buchrieser,Levente Emödy,Gerhard Gottschalk,Jörg Hacker,Ulrich Dobrindt +12 more
TL;DR: Analysis of virulence-associated traits expressed in the two UPEC O6 strains, together with genome comparison, demonstrate the marked genetic and phenotypic variability among UPEC.
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Genome sequence analyses of two isolates from the recent Escherichia coli outbreak in Germany reveal the emergence of a new pathotype: Entero-Aggregative-Haemorrhagic Escherichia coli (EAHEC)
Elzbieta Brzuszkiewicz,Andrea Thürmer,Jörg Schuldes,Andreas Leimbach,Heiko Liesegang,Frauke-Dorothee Meyer,Jürgen Boelter,Heiko Petersen,Gerhard Gottschalk,Rolf Daniel +9 more
TL;DR: The unique combination of genomic features of the German outbreak strain, containing characteristics from pathotypes EAEC and EHEC, suggested that it represents a new pathotype Entero-Aggregative-Haemorrhagic Escherichiacoli (EAHEC).
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The genome of a Bacillus isolate causing anthrax in chimpanzees combines chromosomal properties of B. cereus with B. anthracis virulence plasmids.
Silke R. Klee,Elzbieta Brzuszkiewicz,Herbert Nattermann,Holger Brüggemann,Susann Dupke,Antje Wollherr,Tatjana Franz,Georg Pauli,Bernd Appel,Wolfgang Liebl,Emmanuel Couacy-Hymann,Christophe Boesch,Frauke-Dorothee Meyer,Fabian H. Leendertz,Heinz Ellerbrok,Gerhard Gottschalk,Roland Grunow,Heiko Liesegang +17 more
TL;DR: The sequence of an anthrax causing bacterium possessing both anthrax plasmids that apparently does not belong to the monophyletic group of all so far known B. anthracis strains and that differs in important diagnostic features is described.