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Eman Mohamed Othman Mosaad
Researcher at Queensland University of Technology
Publications - Â 11
Citations - Â 220
Eman Mohamed Othman Mosaad is an academic researcher from Queensland University of Technology. The author has contributed to research in topics: Medicine & Cell culture. The author has an hindex of 4, co-authored 8 publications receiving 151 citations. Previous affiliations of Eman Mohamed Othman Mosaad include Translational Research Institute & Damietta University.
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Journal ArticleDOI
3D Cultures of Prostate Cancer Cells Cultured in a Novel High-Throughput Culture Platform Are More Resistant to Chemotherapeutics Compared to Cells Cultured in Monolayer
Karen F. Chambers,Eman Mohamed Othman Mosaad,Pamela J. Russell,Judith A. Clements,Michael R. Doran +4 more
TL;DR: The results demonstrate that these prostate cancer microaggregates better recapitulate the morphology of prostate tumors compared to 2D and can be used for high-throughput drug testing.
Journal ArticleDOI
The Microwell-mesh: A high-throughput 3D prostate cancer spheroid and drug-testing platform.
Eman Mohamed Othman Mosaad,Eman Mohamed Othman Mosaad,Karen F. Chambers,Katarzyna Futrega,Judith A. Clements,Michael R. Doran +5 more
TL;DR: The results demonstrate that 3D micro-tumours, unlike 2D monolayers, are not hypersensitive to Docetaxel or Abiraterone Acetate, providing a superior platform for the evaluation of sequential drug treatment.
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Bone marrow-derived stem/stromal cells (BMSC) 3D microtissues cultured in BMP-2 supplemented osteogenic induction medium are prone to adipogenesis
Kathryn Futrega,Kathryn Futrega,Eman Mohamed Othman Mosaad,Eman Mohamed Othman Mosaad,Karen F. Chambers,William B. Lott,William B. Lott,Judith A. Clements,Michael R. Doran +8 more
TL;DR: Bone marrow-derived mesenchymal stem/stromal cells may facilitate bone repair through secretion of factors that stimulate endogenous repair processes or through direct contribution to new bone through differentiation into osteoblast-like cells, but high-throughput platforms demonstrate that BMSC in 3D microtissue culture result in tissue compaction, rather than growth.
Journal ArticleDOI
Using high throughput microtissue culture to study the difference in prostate cancer cell behavior and drug response in 2D and 3D co-cultures.
Eman Mohamed Othman Mosaad,Eman Mohamed Othman Mosaad,Eman Mohamed Othman Mosaad,Karen F. Chambers,Katarzyna Futrega,Katarzyna Futrega,Judith A. Clements,Michael R. Doran +7 more
TL;DR: Stromal cell composition and geometry influences PCa cell migration, growth and drug response, and the Microwell-mesh and microtissues are powerful tools to study these complex 3D interactions.
Journal ArticleDOI
The Role(s) of Eicosanoids and Exosomes in Human Parturition.
Eman Mohamed Othman Mosaad,Hassendrini N. Peiris,Olivia J. Holland,Olivia J. Holland,Isabella Morean Garcia,Murray D. Mitchell +5 more
TL;DR: In this paper, a review of the regulation of eicosanoid production, abundance and actions during pregnancy is presented, and the functional significance of placental exosomes is discussed.