E
Emery N. Brown
Researcher at Massachusetts Institute of Technology
Publications - 599
Citations - 37710
Emery N. Brown is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Burst suppression & Spike train. The author has an hindex of 89, co-authored 571 publications receiving 32588 citations. Previous affiliations of Emery N. Brown include Boston University & United States Department of Veterans Affairs.
Papers
More filters
Journal ArticleDOI
Disruption of thalamic functional connectivity is a neural correlate of dexmedetomidine-induced unconsciousness
Oluwaseun Akeju,Marco L. Loggia,Ciprian Catana,Kara J. Pavone,Rafael Vazquez,James Rhee,Violeta Contreras Ramirez,Daniel B. Chonde,David Izquierdo-Garcia,Grae Arabasz,Shirley Hsu,Kathleen Habeeb,Jacob M. Hooker,Vitaly Napadow,Emery N. Brown,Patrick L. Purdon +15 more
TL;DR: It is reported that loss of thalamo-cortical functional connectivity is sufficient to produce unconsciousness and recovery from this state was associated with sustained reduction in cerebral blood flow and restored DMN thalamic functional connectivity.
Journal ArticleDOI
Locally Regularized Spatiotemporal Modeling and Model Comparison for Functional MRI
Patrick L. Purdon,Patrick L. Purdon,Victor Solo,Victor Solo,Robert M. Weisskoff,Emery N. Brown,Emery N. Brown +6 more
TL;DR: This work treats fMRI data analysis as a spatiotemporal system identification problem and addresses issues of model formulation, estimation, and model comparison, presenting a new model that includes a physiologically based hemodynamic response and an empirically derived low-frequency noise model.
Journal ArticleDOI
Neural oscillations demonstrate that general anesthesia and sedative states are neurophysiologically distinct from sleep.
TL;DR: The differences between anesthesia- and sleep-induced altered states from the perspective of neural oscillations are discussed, including the three stages of non-rapid eye movement sleep.
Journal ArticleDOI
Thalamocortical synchronization during induction and emergence from propofol-induced unconsciousness
Francisco J. Flores,Katharine E. Hartnack,Amanda B. Fath,Seong-Eun Kim,Matthew A. Wilson,Emery N. Brown,Patrick L. Purdon +6 more
TL;DR: In vivo evidence in rats that alpha oscillations induced by the commonly used anesthetic drug propofol are synchronized between the thalamus and the medial prefrontal cortex is provided, advancing understanding of anesthesia-induced unconsciousness and altered arousal and further establish principled neurophysiological markers of these states.
Journal ArticleDOI
Circadian rhythms of women with fibromyalgia
Elizabeth B. Klerman,Don L. Goldenberg,Don L. Goldenberg,Emery N. Brown,Anne M. Maliszewski,Gail K. Adler +5 more
TL;DR: Although pain and stiffness were significantly increased in women with fibromyalgia compared with healthy women, there were no circadian rhythms in either parameter, suggesting that abnormalities in circadian rhythmicity are not a primary cause of fibromy arthritis or its symptoms.