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Eneko Larrañeta
Researcher at Queen's University Belfast
Publications - 96
Citations - 5934
Eneko Larrañeta is an academic researcher from Queen's University Belfast. The author has contributed to research in topics: Drug delivery & Transdermal. The author has an hindex of 37, co-authored 96 publications receiving 3598 citations. Previous affiliations of Eneko Larrañeta include Queen's University & University of Navarra.
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Microneedle arrays as transdermal and intradermal drug delivery systems: Materials science, manufacture and commercial development
TL;DR: In this paper, a review of microneedle arrays can increase the number of compounds amenable to transdermal delivery by penetrating the skin's protective barrier, the stratum corneum, and creating a pathway for drug permeation to the dermal tissue below.
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A proposed model membrane and test method for microneedle insertion studies.
Eneko Larrañeta,Jessica Moore,Eva M. Vicente-Pérez,Patricia González-Vázquez,Rebecca E. M. Lutton,A. David Woolfson,Ryan F. Donnelly +6 more
TL;DR: A commercial polymeric film (Parafilm M®, a blend of a hydrocarbon wax and a polyolefin) was evaluated as a model membrane for microneedle (MN) insertion studies as discussed by the authors.
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Microneedles: A New Frontier in Nanomedicine Delivery
TL;DR: This review aims to concisely chart the development of two individual research fields, namely nanomedicines, with specific emphasis on nanoparticles and microparticles, and microneedle technologies, which have, in the recent past, been exploited in combinatorial approaches for the efficient delivery of a variety of medicinal agents across the skin.
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Hydrogel-Forming Microneedles Prepared from ‘‘Super Swelling’’ Polymers Combined with Lyophilised Wafers for Transdermal Drug Delivery
Ryan F. Donnelly,Maelíosa T.C. McCrudden,Ahlam Zaid Alkilani,Eneko Larrañeta,Emma McAlister,Aaron J. Courtenay,Mary-Carmel Kearney,Thakur Raghu Raj Singh,Helen O. McCarthy,Victoria Kett,Ester Caffarel-Salvador,Sharifa Al-Zahrani,A. David Woolfson +12 more
TL;DR: Hydrogel-forming microneedle arrays prepared from “super swelling” polymeric compositions are described, for the first time, and may greatly expand the range of drugs that can be delivered transdermally, to the benefit of patients and industry.
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Implantable Polymeric Drug Delivery Devices: Classification, Manufacture, Materials, and Clinical Applications
TL;DR: An overview of classification of these drug delivery devices; the mechanism of drug release; the materials used for manufacture; the various methods of manufacture; and examples of clinical applications of implantable drug Delivery devices are given.