Eneko Larrañeta

TL;DR: In this paper, a review of microneedle arrays can increase the number of compounds amenable to transdermal delivery by penetrating the skin's protective barrier, the stratum corneum, and creating a pathway for drug permeation to the dermal tissue below.

TL;DR: A commercial polymeric film (Parafilm M®, a blend of a hydrocarbon wax and a polyolefin) was evaluated as a model membrane for microneedle (MN) insertion studies as discussed by the authors.

TL;DR: This review aims to concisely chart the development of two individual research fields, namely nanomedicines, with specific emphasis on nanoparticles and microparticles, and microneedle technologies, which have, in the recent past, been exploited in combinatorial approaches for the efficient delivery of a variety of medicinal agents across the skin.

TL;DR: Hydrogel-forming microneedle arrays prepared from “super swelling” polymeric compositions are described, for the first time, and may greatly expand the range of drugs that can be delivered transdermally, to the benefit of patients and industry.

TL;DR: An overview of classification of these drug delivery devices; the mechanism of drug release; the materials used for manufacture; the various methods of manufacture; and examples of clinical applications of implantable drug Delivery devices are given.