E
Eng-Shang Huang
Researcher at University of North Carolina at Chapel Hill
Publications - 107
Citations - 6870
Eng-Shang Huang is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Human cytomegalovirus & Virus. The author has an hindex of 46, co-authored 107 publications receiving 6735 citations. Previous affiliations of Eng-Shang Huang include National Taiwan University & Academia Sinica.
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Journal ArticleDOI
Congenital Cytomegalovirus Infection
Sergio Stagno,David W. Reynolds,Eng-Shang Huang,Shirley D. Thames,Richard J.H. Smith,Charles A. Alford +5 more
TL;DR: The overall prevalence of congenital cytomegalovirus infection among the offspring of a highly immune young female population was 2.4 percent (23 of 939) as mentioned in this paper.
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Immediate-early gene region of human cytomegalovirus trans-activates the promoter of human immunodeficiency virus.
TL;DR: It is demonstrated that the immediately-early gene region of HCMV, in particular immediate-early region 2, trans-activates the expression of the bacterial gene chloramphenicol acetyltransferase that is fused to the HIV long terminal repeat and carried by plasmid pHIV-CAT.
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Human cytomegalovirus upregulates nf-kappa b activity by transactivating the nf-kappa b p105/p50 and p65 promoters
TL;DR: A model in which the initial induction of NF-kappa B occurs through viral modulation of cellular factors and the sustained levels ofNF-kapp B induction are regulated by a combination of cellular and viral factors is suggested.
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Unique spectrum of activity of 9-[(1,3-dihydroxy-2-propoxy)methyl]-guanine against herpesviruses in vitro and its mode of action against herpes simplex virus type 1
Yung-Chi Cheng,Eng-Shang Huang,Jung-Chung Lin,Eng-Chun Mar,Joseph S. Pagano,Ginger E. Dutschman,Susan P. Grill +6 more
TL;DR: A guanosine analog, 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine (DHPG), was found to inhibit herpes simplex virus type 1 (HSV-1), herpes simpleX virus type 2, cytomegalovirus, and Epstein-Barr virus replication by greater than 50% at concentrations that do not inhibit cell growth in culture.
Journal ArticleDOI
Cytomegalovirus and kaposi's sarcoma in young homosexual men
W. Lawrence Drew,RichardC. Miner,JohnL. Ziegler,JohnH. Gullett,DonaldI. Abrams,M.A. Conant,Eng-Shang Huang,JamesR. Groundwater,Paul A. Volberding,Lawrence Mintz +9 more
TL;DR: Observations suggest an association of CMV with Kaposi's sarcoma, and IgG and IgM antibodies to CMV were detected in 9 out of 9 patients, and normal tissue specimens from 3 KS patients were negative for CMV antigen.