E
Eric G. Neilson
Researcher at Northwestern University
Publications - 247
Citations - 31746
Eric G. Neilson is an academic researcher from Northwestern University. The author has contributed to research in topics: Antigen & Immune system. The author has an hindex of 73, co-authored 247 publications receiving 29759 citations. Previous affiliations of Eric G. Neilson include University of Kansas & University of Michigan.
Papers
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Journal ArticleDOI
Epithelial-mesenchymal transformation of renal tubular epithelial cells in vitro and in vivo.
Book ChapterDOI
Possible mechanisms of renal fibrosis
Journal ArticleDOI
Epithelial differentiation of metanephric mesenchymal cells after stimulation with hepatocyte growth factor or embryonic spinal cord.
TL;DR: Culture of MMR1 cells with embryonic spinal cord leads to the induction of a more differentiated cell phenotype characterized by decreased expression of neural cell adhesion molecule, the appearance of uvomorulin, and the emergence of cytokeratin, all consistent with an evolution toward epithelium.
Journal ArticleDOI
Identification of a novel cis-acting element for fibroblast-specific transcription of the FSP1 gene.
Hirokazu Okada,Theodore M. Danoff,Andreas Fischer,Jesus M. Lopez-Guisa,Frank Strutz,Eric G. Neilson +5 more
TL;DR: A novel domain, FTS-1 (fibroblast transcription site-1; TTGAT from -177 to -173 bp), that specifically interacts with nuclear extracts from fibroblasts is identified and hypothesize that the selective engagement of F TS-1 elements may contribute to the mesenchymal phenotype of fibro Blasts and perhaps other dedifferentiated cells.
Journal ArticleDOI
Pathogenesis of Goodpasture syndrome: a molecular perspective.
TL;DR: The crystal structure of the NC1 domain has revealed how the GP epitopes are sequestered in the native GBM, providing a foundation for the development of new specific therapies for goodpasture syndrome.