E
Eric Glasgow
Researcher at Georgetown University
Publications - 66
Citations - 3769
Eric Glasgow is an academic researcher from Georgetown University. The author has contributed to research in topics: Zebrafish & Supraoptic nucleus. The author has an hindex of 27, co-authored 59 publications receiving 3290 citations. Previous affiliations of Eric Glasgow include Kent State University & State University of New York System.
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Journal ArticleDOI
Understanding behavioral and physiological phenotypes of stress and anxiety in zebrafish
Rupert J. Egan,Carisa L. Bergner,Peter C. Hart,Jonathan Cachat,Peter R. Canavello,Marco Elegante,Salem Elkhayat,Brett Bartels,Anna K. Tien,David Tien,Sopan Mohnot,Esther Beeson,Eric Glasgow,Hakima Amri,Zofia Zukowska,Allan V. Kalueff,Allan V. Kalueff +16 more
TL;DR: Zebrafish models of stress by analyzing how environmental and pharmacological manipulations affect their behavioral and physiological phenotypes are validated and alterations in whole-body cortisol levels in zebrafish parallel behavioral indices of anxiety are shown.
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Motoneuron fate specification revealed by patterned LIM homeobox gene expression in embryonic zebrafish
Bruce Appel,Vladimir Korzh,Eric Glasgow,Stefan Thor,Thomas Edlund,Igor B. Dawid,Judith S. Eisen +6 more
TL;DR: The patterned distribution of different primary motoneuronal types within the zebrafish spinal cord follows the patterned expression of LIM homeobox genes, and this reflects a highly resolved system of positional information controlling gene transcription.
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The STAT3 inhibitor NSC 74859 is effective in hepatocellular cancers with disrupted TGF-β signaling
Ling Lin,Rupen Amin,G. I. Gallicano,Eric Glasgow,Wilma Jogunoori,J. M. Jessup,Michael Zasloff,John L. Marshall,K. Shetty,Lynt B. Johnson,Lopa Mishra,Aiwu R. He +11 more
TL;DR: It is concluded that inhibiting interleukin 6 (IL6)/STAT3 in HCCs with inactivation of the TGF-β/β2SP pathway is an effective approach in management of H CCs.
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The mitochondrial citrate transporter, CIC, is essential for mitochondrial homeostasis.
Olga Catalina-Rodriguez,Vamsi K. Kolukula,York Tomita,Anju Preet,Ferdinando Palmieri,Anton Wellstein,Stephen W. Byers,Amato J. Giaccia,Eric Glasgow,Chris Albanese,Maria Laura Avantaggiati +10 more
TL;DR: It is reported here that in tumor cells CIC maintains mitochondrial integrity and bioenergetics, protects from mitochondrial damage and circumvents mitochondrial depletion via autophagy, hence promoting proliferation and implying that this protein is a therapeutic target in cancer and likely, in other human diseases.
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Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells.
Gülay Bulut,Sung-Hyeok Hong,Kevin Chen,Em M. Beauchamp,Said Rahim,Gw W. Kosturko,Eric Glasgow,Sivanesan Dakshanamurthy,Hyun-Shik Lee,I Daar,Ja A. Toretsky,Chand Khanna,Aykut Üren +12 more
TL;DR: Two small molecule inhibitors, NSC305787 and NSC668394, demonstrate a novel targeted therapy that directly inhibits ezrin protein as an approach to prevent tumor metastasis and cause a unique developmental defect consistent with reduced cell motility in zebrafish.