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Salem Elkhayat
Researcher at Tulane University
Publications - Â 13
Citations - Â 2746
Salem Elkhayat is an academic researcher from Tulane University. The author has contributed to research in topics: Zebrafish & Social defeat. The author has an hindex of 11, co-authored 13 publications receiving 2353 citations.
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Journal ArticleDOI
Understanding behavioral and physiological phenotypes of stress and anxiety in zebrafish
Rupert J. Egan,Carisa L. Bergner,Peter C. Hart,Jonathan Cachat,Peter R. Canavello,Marco Elegante,Salem Elkhayat,Brett Bartels,Anna K. Tien,David Tien,Sopan Mohnot,Esther Beeson,Eric Glasgow,Hakima Amri,Zofia Zukowska,Allan V. Kalueff,Allan V. Kalueff +16 more
TL;DR: Zebrafish models of stress by analyzing how environmental and pharmacological manipulations affect their behavioral and physiological phenotypes are validated and alterations in whole-body cortisol levels in zebrafish parallel behavioral indices of anxiety are shown.
Journal ArticleDOI
Measuring behavioral and endocrine responses to novelty stress in adult zebrafish
Jonathan Cachat,Adam Stewart,Leah Grossman,Siddharth Gaikwad,Ferdous Kadri,Kyung Min Chung,Nadine Wu,Keith Wong,Sudipta Roy,Christopher Suciu,Jason Goodspeed,Marco Elegante,Brett Bartels,Salem Elkhayat,David Tien,Julia Tan,Ashley Denmark,Thomas Gilder,Evan J. Kyzar,John DiLeo,Kevin Frank,Katie Chang,Eli Utterback,Peter C. Hart,Allan V. Kalueff +24 more
TL;DR: This protocol is an easy, inexpensive and effective alternative to other methods of measuring stress responses in zebrafish, thus enabling the rapid acquisition and analysis of large amounts of data.
Journal ArticleDOI
Analyzing habituation responses to novelty in zebrafish (Danio rerio).
Keith Wong,Marco Elegante,Brett Bartels,Salem Elkhayat,David Tien,Sudipta Roy,Jason Goodspeed,Chris Suciu,Julia Tan,Chelsea Grimes,Amanda Chung,Michael Rosenberg,Siddharth Gaikwad,Ashley Denmark,Andrew Jackson,Ferdous Kadri,Kyung Min Chung,Adam Stewart,Tom Gilder,Esther Beeson,Ivan Zapolsky,Nadine Wu,Jonathan Cachat,Allan V. Kalueff +23 more
TL;DR: It is shown that chronic ethanol and fluoxetine treatments improved intra-session habituation in zebrafish and selected anxiogenic drugs (caffeine, pentylenetetrazole), as well as stress-inducing alarm pheromone, attenuated zebra fish habituation.
Journal ArticleDOI
Characterization of behavioral and endocrine effects of LSD on zebrafish.
Leah Grossman,Eli Utterback,Adam Stewart,Siddharth Gaikwad,Kyung Min Chung,Christopher Suciu,Keith Wong,Marco Elegante,Salem Elkhayat,Julia Tan,Thomas Gilder,Nadine Wu,John DiLeo,Jonathan Cachat,Allan V. Kalueff +14 more
TL;DR: Overall, the findings show sensitivity of zebrafish to LSD action, and support the use ofZebrafish models to study hallucinogenic drugs of abuse.
Journal ArticleDOI
Modeling withdrawal syndrome in zebrafish.
Jonathan Cachat,Peter R. Canavello,Marco Elegante,Brett Bartels,Peter C. Hart,Peter C. Hart,Carisa L. Bergner,Rupert J. Egan,Ashley Duncan,David Tien,Amanda Chung,Keith Wong,Jason Goodspeed,Julia Tan,Chelsea Grimes,Salem Elkhayat,Christopher Suciu,Michael Rosenberg,Kyung Min Chung,Ferdous Kadri,Sudipta Roy,Siddharth Gaikwad,Adam Stewart,Ivan Zapolsky,Thomas Gilder,Sopan Mohnot,Esther Beeson,Hakima Amri,Zofia Zukowska,R. Denis Soignier,Allan V. Kalueff,Allan V. Kalueff +31 more
TL;DR: Overall, discontinuation of ethanol, diazepam and morphine produced anxiogenic-like behavioral or endocrine responses, demonstrating the utility of zebrafish in translational research of withdrawal syndrome.