E
Eric Henderson
Researcher at Dartmouth–Hitchcock Medical Center
Publications - 219
Citations - 8572
Eric Henderson is an academic researcher from Dartmouth–Hitchcock Medical Center. The author has contributed to research in topics: Medicine & Engineering. The author has an hindex of 45, co-authored 197 publications receiving 7780 citations. Previous affiliations of Eric Henderson include Dartmouth College & University of California, Los Angeles.
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Book ChapterDOI
Ribosome Structure, Function, and Evolution: Mapping Ribosomal RNA, Proteins, and Functional Sites in Three Dimensions
TL;DR: Comparison studies of ribosomes have revealed some of the early steps in the evolution of Ribosomes and of the cells that contain them.
Journal ArticleDOI
Mapping evolution with ribosome structure: intralineage constancy and interlineage variation.
TL;DR: The intralineage conservation of ribosomal three-dimensional structure is interpreted as forming a phylogenetic basis for regarding archaebacteria, eubacteria, and eukaryotes as primitive lines.
Journal ArticleDOI
Detection and Quantification of Protein Biomarkers from Fewer than 10 Cells
Saju Nettikadan,Korinna M Radke,James C. Johnson,Juntao Xu,Michael Lynch,Curtis Mosher,Eric Henderson +6 more
TL;DR: The construction of ultramicroarrays for the detection of interleukin-6 and prostate-specific antigen (PSA), a widely used biomarker for prostate cancer screening, were constructed and were found to have a high specificity and sensitivity with detection levels using purified proteins in the attomole range.
Journal ArticleDOI
DNA hybridization electron microscopy: ribosomal RNA nucleotides 1392-1407 are exposed in the cleft of the small subunit.
TL;DR: The location of this region, which has been crosslinked to the anticodon of a peptidyl-site-bound tRNA, indicates that this part of the cleft of the small subunit has a similar three-dimensional organization in phylogenetically diverse organisms and suggests that it is the site of the codon-anticodon interaction.
Journal ArticleDOI
A new ribosome structure.
Eric Henderson,Melanie I. Oakes,Michael W. Clark,James A. Lake,A. T. Matheson,Wolfram Zillig +5 more
TL;DR: Ribosomes derived from the sulfur-dependent archaebacteria are structurally distinct from those types found in ribosomes from eubacteria, eukaryotes, and other archaEBacteria, but each type also has additional independent structural features that are consistent with other molecular biological properties peculiar to these organisms.