E
Erik W. Dent
Researcher at University of Wisconsin-Madison
Publications - 72
Citations - 7828
Erik W. Dent is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Growth cone & Axon. The author has an hindex of 35, co-authored 68 publications receiving 7207 citations. Previous affiliations of Erik W. Dent include Colgate University & Syracuse University.
Papers
More filters
Journal ArticleDOI
Cytoskeletal dynamics and transport in growth cone motility and axon guidance
Erik W. Dent,Frank B. Gertler +1 more
TL;DR: A working model for cytoskeletal regulation of directed axon outgrowth is presented and an important goal for the future will be to understand the coordinated response of the cytoskeleton to signaling cascades induced by guidance receptor activation.
Journal ArticleDOI
Ena/VASP proteins: regulators of the actin cytoskeleton and cell migration.
TL;DR: Phosphorylation by PKA/PKG serine/threonine kinases appears to modulate Ena/VASP function within cells, although the mechanism underlying this regulation remains to be determined.
Journal ArticleDOI
The Growth Cone Cytoskeleton in Axon Outgrowth and Guidance
TL;DR: The role of cytoskeletal-associated proteins, as well as the cytoskeleton itself in axon outgrowth and guidance, is the subject of this article.
Journal ArticleDOI
Axon branching requires interactions between dynamic microtubules and actin filaments.
Erik W. Dent,Katherine Kalil +1 more
TL;DR: Interactions between dynamic microtubules and actin filaments are required for axon branching and directed axon outgrowth in cortical growth cones and axons undergoing branching.
Journal ArticleDOI
Filopodia are required for cortical neurite initiation
Erik W. Dent,Erik W. Dent,Adam V. Kwiatkowski,Leslie M. Mebane,Ulrike Philippar,Melanie Barzik,Douglas A. Rubinson,Stephanie L. Gupton,J. Edward van Veen,Craig Furman,Jiangyang Zhang,Arthur S. Alberts,Susumu Mori,Frank B. Gertler +13 more
TL;DR: It is reported that neuritogenesis in Ena/VASP-null neurons can be rescued by restoring filopodia formation through ectopic expression of the actin nucleating protein mDia2, and that laminin, which promotes the formation of filipodia-like actin-rich protrusions, rescues neuritogenic in EnA/VasP-deficient neurons.