E
Erin E. McClelland
Researcher at Middle Tennessee State University
Publications - 38
Citations - 4751
Erin E. McClelland is an academic researcher from Middle Tennessee State University. The author has contributed to research in topics: Cryptococcus neoformans & Virulence. The author has an hindex of 18, co-authored 35 publications receiving 4517 citations. Previous affiliations of Erin E. McClelland include Albert Einstein College of Medicine & The Commonwealth Medical College.
Papers
More filters
Journal ArticleDOI
A novel MHC class I–like gene is mutated in patients with hereditary haemochromatosis
John N. Feder,Andreas Gnirke,Winston Thomas,Zenta Tsuchihashi,David A. Ruddy,A. Basava,F. Dormishian,R. Domingo,Michael C. Ellis,A. Fullan,L.M. Hinton,Norman Jones,B.E. Kimmel,Gregory S. Kronmal,Peter M. San Francisco Lauer,V.K. Lee,Deborah B. Loeb,Felipa A. Mapa,Erin E. McClelland,Nicole C. Meyer,Gabe Mintier,N. Moeller,T. E. Moore,E. Morikang,Cynthia E. Prass,Leah Quintana,Steven M. Starnes,Randall C. Schatzman,K.J. Brunke,Dennis Drayna,Neil Risch,Bruce R. Bacon,Roger K. Wolff +32 more
TL;DR: Using linkage-disequilibrium and full haplotype analysis, this paper identified a 250-kilobase region more than 3 megabases telomeric of the major histocompatibility complex (MHC) that is identical-by-descent in 85% of patient chromosomes.
Journal ArticleDOI
Major Histocompatibility Complex Heterozygote Superiority during Coinfection
TL;DR: This is the first experimental evidence for MHC heterozygote superiority against multiple pathogens, a mechanism that would contribute to the evolution of MHC diversity and explain the persistence of alleles conferring susceptibility to disease.
Journal ArticleDOI
Gender Specific Differences in the Immune Response to Infection
TL;DR: Gender specific differences seen in infections caused by bacteria, fungi, parasites and viruses appear to be dependent on the microbe causing the infection, as not every infection with a specific microbial type results in increased susceptibility of one gender over the other.
Journal ArticleDOI
A 1.1-mb transcript map of the hereditary hemochromatosis locus
David A. Ruddy,Gregory S. Kronmal,Vincent K. Lee,Gabriel Mintier,Leah Quintana,Rodolfo Domingo,Nicole C. Meyer,Alivelu Irrinki,Erin E. McClelland,Amy Fullan,Felipa A. Mapa,Theodore Moore,Winston Thomas,Deborah B. Loeb,Cyrus L. Harmon,Zenta Tsuchihashi,Roger K. Wolff,Randall C. Schatzman,John N. Feder +18 more
TL;DR: An analysis of the four approaches for gene finding and conclude that direct selection provides the most effective probes for cDNA screening, and that as much as 30% of ESTs in this 1.1-Mb region may be derived from noncoding genomic DNA.
Journal ArticleDOI
Ab binding alters gene expression in Cryptococcus neoformans and directly modulates fungal metabolism
Erin E. McClelland,André Moraes Nicola,André Moraes Nicola,Rafael Prados-Rosales,Arturo Casadevall +4 more
TL;DR: What is believed to be a new mode of action for Ab-mediated immunity is suggested and the possibility that immunoglobulins mediate cross talk between microbes and hosts through their effects on microbial metabolism is raised.