G
Gregory S. Kronmal
Researcher at Bio-Rad Laboratories
Publications - 8
Citations - 3992
Gregory S. Kronmal is an academic researcher from Bio-Rad Laboratories. The author has contributed to research in topics: Gene & Candidate gene. The author has an hindex of 6, co-authored 8 publications receiving 3915 citations.
Papers
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Journal ArticleDOI
A novel MHC class I–like gene is mutated in patients with hereditary haemochromatosis
John N. Feder,Andreas Gnirke,Winston Thomas,Zenta Tsuchihashi,David A. Ruddy,A. Basava,F. Dormishian,R. Domingo,Michael C. Ellis,A. Fullan,L.M. Hinton,Norman Jones,B.E. Kimmel,Gregory S. Kronmal,Peter M. San Francisco Lauer,V.K. Lee,Deborah B. Loeb,Felipa A. Mapa,Erin E. McClelland,Nicole C. Meyer,Gabe Mintier,N. Moeller,T. E. Moore,E. Morikang,Cynthia E. Prass,Leah Quintana,Steven M. Starnes,Randall C. Schatzman,K.J. Brunke,Dennis Drayna,Neil Risch,Bruce R. Bacon,Roger K. Wolff +32 more
TL;DR: Using linkage-disequilibrium and full haplotype analysis, this paper identified a 250-kilobase region more than 3 megabases telomeric of the major histocompatibility complex (MHC) that is identical-by-descent in 85% of patient chromosomes.
Journal ArticleDOI
Cloning of a unique lipase from endothelial cells extends the lipase gene family
Ken-ichi Hirata,Helén L. Dichek,Joseph A. Cioffi,Sungshin Y. Choi,Nicholas J. Leeper,Leah Quintana,Gregory S. Kronmal,Allen D. Cooper,Thomas Quertermous +8 more
TL;DR: Its tissue-restricted pattern of expression and its ability to be expressed by endothelial cells, suggests that endothelial cell-derived lipase may have unique functions in lipoprotein metabolism and in vascular disease.
Journal ArticleDOI
A 1.1-mb transcript map of the hereditary hemochromatosis locus
David A. Ruddy,Gregory S. Kronmal,Vincent K. Lee,Gabriel Mintier,Leah Quintana,Rodolfo Domingo,Nicole C. Meyer,Alivelu Irrinki,Erin E. McClelland,Amy Fullan,Felipa A. Mapa,Theodore Moore,Winston Thomas,Deborah B. Loeb,Cyrus L. Harmon,Zenta Tsuchihashi,Roger K. Wolff,Randall C. Schatzman,John N. Feder +18 more
TL;DR: An analysis of the four approaches for gene finding and conclude that direct selection provides the most effective probes for cDNA screening, and that as much as 30% of ESTs in this 1.1-Mb region may be derived from noncoding genomic DNA.
Journal ArticleDOI
HLA class II haplotype and sequence analysis support a role for DQ in narcolepsy
Michael C. Ellis,Angela H. Hetisimer,David A. Ruddy,Sherry L. Hansen,Gregory S. Kronmal,Erin E. McClelland,Leah Quintana,Dennis Drayna,Michael S. Aldrich,Emmanuel Mignot +9 more
TL;DR: Results from a systematic haplotype and sequencing analysis of the HLA-DR and -DQ region in patients with narcolepsy are consistent with other studies, suggesting that the Hla-DQ genes themselves are among the predisposing factors in narcoLEpsy.
Patent
Polymorphisms and new genes in the region of the human hemochromatosis gene
John N. Feder,Gregory S. Kronmal,Peter M. San Francisco Lauer,David A. Ruddy,Winston J. Thomas,Zenta Tsuchihashi,Roger K. Wolff +6 more
TL;DR: In this paper, a fine structure map of the 1 megabase region surrounding the HFE gene is provided, along with 235 kb of DNA sequence and 8 loci corresponding to candidate genes within this region.