E
Erin Gardiner
Researcher at University of Newcastle
Publications - 12
Citations - 1277
Erin Gardiner is an academic researcher from University of Newcastle. The author has contributed to research in topics: Gene expression profiling & Gene silencing. The author has an hindex of 10, co-authored 12 publications receiving 1145 citations.
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Journal ArticleDOI
Schizophrenia is associated with an increase in cortical microRNA biogenesis.
TL;DR: A significant schizophrenia-associated increase in global microRNA expression was associated with an elevation of primary microRNA processing and corresponded with an increase in the microprocessor component DGCR8.
Journal ArticleDOI
Dysregulation of miRNA 181b in the temporal cortex in schizophrenia
Natalie J. Beveridge,Paul A. Tooney,Adam P. Carroll,Erin Gardiner,Nikola A. Bowden,Rodney J. Scott,Nham Tran,Irina Dedova,Murray J. Cairns +8 more
TL;DR: Analysis of global microRNA expression in postmortem cortical grey matter from the superior temporal gyrus revealed significant up-regulation of miR-181b expression in schizophrenia.
Journal ArticleDOI
Imprinted DLK1-DIO3 region of 14q32 defines a schizophrenia-associated miRNA signature in peripheral blood mononuclear cells.
Erin Gardiner,Natalie J. Beveridge,Jing Qin Wu,Vaughan J. Carr,Rodney J. Scott,Paul A. Tooney,Murray J. Cairns +6 more
TL;DR: Investigation of the miRNA expression profile of peripheral blood mononuclear cells from 112 patients with schizophrenia and 76 non-psychiatric controls revealed a pattern of differentially expressed miRNA in PBMCs that may be indicative of significant underlying genetic or epigenetic alteration associated with schizophrenia.
Journal ArticleDOI
Gene expression analysis reveals schizophrenia-associated dysregulation of immune pathways in peripheral blood mononuclear cells
Erin Gardiner,Murray J. Cairns,Bing Liu,Natalie J. Beveridge,Vaughan J. Carr,Brian Kelly,Rodney J. Scott,Paul A. Tooney +7 more
TL;DR: Genome-wide expression analysis of PBMCs from individuals with schizophrenia was characterized by the alteration of genes with immune system function, supporting the hypothesis that the disorder has a significant immunological component in its etiology.
Journal ArticleDOI
Transcriptome-wide mega-analyses reveal joint dysregulation of immunologic genes and transcription regulators in brain and blood in schizophrenia
Jonathan L. Hess,Jonathan L. Hess,Daniel S. Tylee,Daniel S. Tylee,Rahul Barve,Rahul Barve,Simone de Jong,Simone de Jong,Roel A. Ophoff,Roel A. Ophoff,Nishantha Kumarasinghe,Paul A. Tooney,Ulrich Schall,Erin Gardiner,Natalie J. Beveridge,Rodney J. Scott,S.G. Yasawardene,Antionette Perera,Jayan Mendis,Vaughan J. Carr,Brian Kelly,Murray J. Cairns,Ming T. Tsuang,Ming T. Tsuang,Stephen J. Glatt,Stephen J. Glatt +25 more
TL;DR: Two mega-analyses of a combined set of microarray data from postmortem prefrontal cortices and ex-vivo blood tissues provide an informative atlas for future pathophysiologic and biomarker studies of schizophrenia.