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Natalie J. Beveridge
Researcher at University of Newcastle
Publications - 23
Citations - 2451
Natalie J. Beveridge is an academic researcher from University of Newcastle. The author has contributed to research in topics: microRNA & Gene expression profiling. The author has an hindex of 18, co-authored 23 publications receiving 2188 citations. Previous affiliations of Natalie J. Beveridge include University of Sydney.
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Journal ArticleDOI
Schizophrenia is associated with an increase in cortical microRNA biogenesis.
TL;DR: A significant schizophrenia-associated increase in global microRNA expression was associated with an elevation of primary microRNA processing and corresponded with an increase in the microprocessor component DGCR8.
Journal ArticleDOI
The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing.
Guy Barry,James Briggs,Darya P. Vanichkina,Erin M. Poth,Natalie J. Beveridge,Vikram S. Ratnu,Sam P Nayler,Katia Nones,Jianfei Hu,Timothy W. Bredy,Shinichi Nakagawa,Frank Rigo,Ryan J. Taft,Murray J. Cairns,Seth Blackshaw,Ernst J. Wolvetang,John S. Mattick,John S. Mattick,John S. Mattick +18 more
TL;DR: It is shown that long non-coding RNAs (lncRNAs) are dynamically regulated by neuronal activation, including acute downregulation of the lncRNA Gomafu, previously implicated in brain and retinal development, and that Gomafi is downregulated in post-mortem cortical gray matter from the superior temporal gyrus in SZ.
Journal ArticleDOI
Dysregulation of miRNA 181b in the temporal cortex in schizophrenia
Natalie J. Beveridge,Paul A. Tooney,Adam P. Carroll,Erin Gardiner,Nikola A. Bowden,Rodney J. Scott,Nham Tran,Irina Dedova,Murray J. Cairns +8 more
TL;DR: Analysis of global microRNA expression in postmortem cortical grey matter from the superior temporal gyrus revealed significant up-regulation of miR-181b expression in schizophrenia.
Journal ArticleDOI
Upregulation of dicer and microRNA expression in the dorsolateral prefrontal cortex Brodmann area 46 in schizophrenia.
TL;DR: The results suggest that schizophrenia is associated with altered miRNA biogenesis and expression, which might have important implications in the complex pathophysiology of the disorder.
Journal ArticleDOI
Imprinted DLK1-DIO3 region of 14q32 defines a schizophrenia-associated miRNA signature in peripheral blood mononuclear cells.
Erin Gardiner,Natalie J. Beveridge,Jing Qin Wu,Vaughan J. Carr,Rodney J. Scott,Paul A. Tooney,Murray J. Cairns +6 more
TL;DR: Investigation of the miRNA expression profile of peripheral blood mononuclear cells from 112 patients with schizophrenia and 76 non-psychiatric controls revealed a pattern of differentially expressed miRNA in PBMCs that may be indicative of significant underlying genetic or epigenetic alteration associated with schizophrenia.