Erini Dermitzaki

TL;DR: The data suggest that adiponectin constant presence in the circulation in high levels (in lean subjects) renders macrophages resistant to pro-inflammatory stimuli, including its own.

TL;DR: CRH promotes PC12 apoptosis via the CRH type 1 receptor, which induces Fas ligand production via activation of p38, which promoted a rapid and transient activation of ERK1/2, which was not necessary for either CRH-induced apoptosis or Fas ligands production.

TL;DR: The data suggest that CRF peptides play an important role on macrophage function, and augment the effect of LPS by inducing Tlr4 gene expression, through CRF2, via activation of the transcription factors PU.1 and AP-1.

TL;DR: This is the first report suggesting that CRF1 and CRF2 agonists exert a biphasic effect on macrophage, and the reported anti‐inflammatory effect of CRF‐peptides appears to involve macrophages and is confined at the early stage of inflammation.

TL;DR: The data presented here suggest that endometrial CRH regulates the production of local modulators of decidualization, i.e. PGE(2), IL-1 and IL-6, and postulate that, through the regulation of these factors, CRH acts as a local fine-tuner of decdualization initiated by progesterone.