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Erland Arning
Researcher at Baylor University
Publications - 38
Citations - 893
Erland Arning is an academic researcher from Baylor University. The author has contributed to research in topics: Homocysteine & Hyperhomocysteinemia. The author has an hindex of 17, co-authored 38 publications receiving 777 citations. Previous affiliations of Erland Arning include Veterans Health Administration & Roy J. and Lucille A. Carver College of Medicine.
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Journal ArticleDOI
Enhanced susceptibility to arterial thrombosis in a murine model of hyperhomocysteinemia
Sanjana Dayal,Katina M. Wilson,Katina M. Wilson,Katina M. Wilson,Lorie Leo,Lorie Leo,Lorie Leo,Erland Arning,Erland Arning,Erland Arning,Teodoro Bottiglieri,Teodoro Bottiglieri,Teodoro Bottiglieri,Steven R. Lentz,Steven R. Lentz,Steven R. Lentz +15 more
TL;DR: It is concluded that hyperhomocysteinemia enhances susceptibility to arterial thrombosis through a mechanism that is not caused by loss of endothelium-derived nitric oxide but may involve oxidative stress and impairment of the protein C anticoagulant pathway.
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Hyperhomocysteinemia Potentiates Hyperglycemia-induced Inflammatory Monocyte Differentiation and Atherosclerosis
Pu Fang,Daqing Zhang,Zhongjian Cheng,Chenghui Yan,Xiaohua Jiang,Warren D. Kruger,Shu Meng,Erland Arning,Teodoro Bottiglieri,Eric T. Choi,Yaling Han,Xiaofeng Yang,Hong Wang +12 more
TL;DR: It is demonstrated that HHcy and HG accelerated atherosclerosis and increased lesion monocytes and macrophages and further increased inflammatory MC and MØ levels in peripheral tissues and HHcy-lowering reversed circulating mononuclear cells, MC, and inflammatoryMC and MC-derived M Ø levels.
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Cerebral Vascular Dysfunction in Methionine Synthase–Deficient Mice
Sanjana Dayal,Angela M. Devlin,Ryan B. McCaw,Mei-Lan Liu,Erland Arning,Teodoro Bottiglieri,Barry Shane,Frank M. Faraci,Steven R. Lentz +8 more
TL;DR: It is demonstrated that defective homocysteine remethylation caused by deficiency of either MS or folate produces oxidative stress and endothelial dysfunction in the cerebral microcirculation of mice.
Journal ArticleDOI
Effects of exercise on emerging and traditional cardiovascular risk factors.
Glen E. Duncan,Michael G. Perri,Stephen D. Anton,Marian C. Limacher,A. Daniel Martin,David T. Lowenthal,David T. Lowenthal,Erland Arning,Teodoro Bottiglieri,Peter W. Stacpoole +9 more
TL;DR: Although frequent bouts of higher intensity exercise were particularly effective in reducing fasting insulin and improving fitness, they resulted in slightly increased homocysteine levels.
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Changes in Methionine Metabolism and Histone H3 Trimethylation Are Linked to Mitochondrial Defects in Multiple Sclerosis.
Naveen Kumar Singhal,Shuo Li,Erland Arning,Kholoud Alkhayer,Robert Clements,Zachary Sarcyk,Rohan S. Dassanayake,Nicola E. Brasch,Ernest J. Freeman,Teodoro Bottiglieri,Jennifer McDonough +10 more
TL;DR: It is found that vitamin B12-dependent methionine metabolism is dysregulated in the MS brain and concentrations of the methyl donor betaine are decreased in MS cortex and are correlated with reduced levels of the histone H3 methyl mark H3K4me3 in neurons.