E
Esa Vanhala
Researcher at Finnish Institute of Occupational Health
Publications - 44
Citations - 1899
Esa Vanhala is an academic researcher from Finnish Institute of Occupational Health. The author has contributed to research in topics: Asbestos & Genotoxicity. The author has an hindex of 24, co-authored 41 publications receiving 1686 citations.
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Journal ArticleDOI
Genotoxicity of nanomaterials: DNA damage and micronuclei induced by carbon nanotubes and graphite nanofibres in human bronchial epithelial cells in vitro.
Hanna K. Lindberg,Ghita C.-M. Falck,Satu Suhonen,Minnamari Vippola,Minnamari Vippola,Esa Vanhala,Julia Catalán,Julia Catalán,Kai Savolainen,Hannu Norppa +9 more
TL;DR: The results suggest that both CNTs and GNFs are genotoxic in human bronchial epithelial BEAS 2B cells in vitro, and this activity may be due to the fibrous nature of these carbon nanomaterials with a possible contribution by catalyst metals present in the materials.
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Genotoxic effects of nanosized and fine TiO2.
Ghita C.-M. Falck,Hanna K. Lindberg,Satu Suhonen,Minnamari Vippola,Esa Vanhala,Julia Catalán,Kai Savolainen,Hannu Norppa +7 more
TL;DR: The studies in human bronchial epithelial BEAS 2B cells showed that uncoated nanosized anatase TiO2 and fine rutileTiO2 are more efficient than SiO 2-coated Nanosized rutiles TiO 2 in inducing DNA damage, whereas only nanosize anatase is able to slightly induce micronuclei.
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Airway Exposure to Silica-Coated TiO2 Nanoparticles Induces Pulmonary Neutrophilia in Mice
Elina M. Rossi,Lea Pylkkänen,Antti Joonas Koivisto,Minnamari Vippola,Minnamari Vippola,Keld Alstrup Jensen,Mirella Miettinen,Kristiina Sirola,Heli Nykäsenoja,Piia Karisola,Tuula Stjernvall,Esa Vanhala,Mirja Kiilunen,Pertti Pasanen,Maija Mäkinen,Kaarle Hämeri,Kaarle Hämeri,Jorma Joutsensaari,Timo Tuomi,Jorma Jokiniemi,Jorma Jokiniemi,Henrik Wolff,Kai Savolainen,Sampsa Matikainen,Harri Alenius +24 more
TL;DR: Interestingly, the level of lung inflammation could not be explained by the surface area of the particles, their primary or agglomerate particle size, or radical formation capacity but is rather explained byThe surface coating.
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Genotoxic and immunotoxic effects of cellulose nanocrystals in vitro
Julia Catalán,Julia Catalán,Marit Ilves,Hilkka Järventaus,Kati-Susanna Hannukainen,Eero Kontturi,Esa Vanhala,Harri Alenius,Kai Savolainen,Hannu Norppa +9 more
TL;DR: Results show that nanosized CNC is neither genotoxic nor immunotoxic under the conditions tested, whereas non‐nanosized MCC is able to induce an inflammatory response.
Journal ArticleDOI
Influence of relative humidity and physical load during storage on dustiness of inorganic nanomaterials: implications for testing and risk assessment
Marcus Levin,Elena Rojas,Esa Vanhala,Minnamari Vippola,Minnamari Vippola,Biase Liguori,Kirsten Inga Kling,Ismo K. Koponen,Kristian Mølhave,Timo Tuomi,Danijela Gregurec,Sergio Moya,Keld Alstrup Jensen +12 more
TL;DR: In this article, the effects of storage conditions such as relative humidity and physical loading on the dustiness of five inorganic metal oxide nanostructured powder materials were investigated using a down-scaled EN15051 rotating drum.