E
Estelle Lauer
Researcher at University of Lausanne
Publications - 25
Citations - 623
Estelle Lauer is an academic researcher from University of Lausanne. The author has contributed to research in topics: Physical exercise & Hippocampus. The author has an hindex of 12, co-authored 24 publications receiving 503 citations. Previous affiliations of Estelle Lauer include American Board of Legal Medicine & University of Geneva.
Papers
More filters
Journal ArticleDOI
Automated system for on-line desorption of dried blood spots applied to LC/MS/MS pharmacokinetic study of flurbiprofen and its metabolite
Julien Déglon,Aurélien Thomas,Youssef Daali,Youssef Daali,Estelle Lauer,Caroline Flora Samer,Caroline Flora Samer,Jules Alexandre Desmeules,Jules Alexandre Desmeules,Pierre Dayer,Pierre Dayer,Patrice Mangin,Christian Staub,Christian Staub +13 more
TL;DR: The automated system described in this article represents an efficient tool for the LC/MS/MS analysis of DBS samples in many bioanalytical applications and showed good precision, trueness, and linearity over the expected concentration range.
Journal ArticleDOI
Drug vaping applied to cannabis: Is “Cannavaping” a therapeutic alternative to marijuana?
Vincent Varlet,Nicolas Concha-Lozano,Aurélie Berthet,Gregory Plateel,Bernard Favrat,Bernard Favrat,Mariangela De Cesare,Estelle Lauer,Marc Augsburger,Aurélien Thomas,Aurélien Thomas,Christian Giroud +11 more
TL;DR: The results showed that illegal cannavaping would be subjected to marginal development due to the poor solubility of BHO in commercial liquid refills (especially those with high glycerin content), which prevents the manufacture of liquid refill with high BHO concentrations adopted by most recreational users of cannabis.
Journal ArticleDOI
Diabetes Mellitus Is Associated With Reduced High-Density Lipoprotein Sphingosine-1-Phosphate Content and Impaired High-Density Lipoprotein Cardiac Cell Protection
Jonas Brinck,Aurélien Thomas,Estelle Lauer,François R Jornayvaz,Marie-Claude Brulhart-Meynet,Jean-Christophe Prost,Zoltan Pataky,Patrik Löfgren,Johan Hoffstedt,Mats Eriksson,Camilla Pramfalk,Sandrine Morel,Brenda R. Kwak,Miranda Van Eck,Richard W. James,Miguel Frias +15 more
TL;DR: It is demonstrated that glycation can reduce the S1P content of HDL, leading to increased cardiomyocyte cell death because of less effective activation of intracellular survival pathways.
Journal ArticleDOI
Comparison of cannabinoid concentrations in oral fluid and whole blood between occasional and regular cannabis smokers prior to and after smoking a cannabis joint
Marie Fabritius,Haithem Chtioui,Giovanni Battistella,Jean-Marie Annoni,Kim Dao,Bernard Favrat,Eleonora Fornari,Estelle Lauer,Philippe Maeder,Christian Giroud +9 more
TL;DR: It is found that THC, and also THC-A, shows a sharp, high concentration peak just after smoking, with a rapid decrease in these levels within 3 h, with no obvious differences found between both groups concerning THC median maximum concentrations measured either in blood or in OF.
Journal ArticleDOI
Use of the dried blood spot sampling process coupled with fast gas chromatography and negative-ion chemical ionization tandem mass spectrometry: application to fluoxetine, norfluoxetine, reboxetine, and paroxetine analysis.
Julien Déglon,Julien Déglon,Estelle Lauer,Estelle Lauer,Aurélien Thomas,Aurélien Thomas,Patrice Mangin,Christian Staub,Christian Staub +8 more
TL;DR: The validated DBS method combines an extractive—derivative single step with a fast and sensitive GC-NICI-MS-MS technique and was successfully applied to a pharmacokinetic investigation performed on a healthy volunteer after oral administration of a single 40-mg dose of fluoxetine.