E
Eulália Galhano
Researcher at University of Aveiro
Publications - 15
Citations - 825
Eulália Galhano is an academic researcher from University of Aveiro. The author has contributed to research in topics: Pregnancy & Excretion. The author has an hindex of 11, co-authored 13 publications receiving 717 citations.
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Journal ArticleDOI
Metabolic Biomarkers of Prenatal Disorders: An Exploratory NMR Metabonomics Study of Second Trimester Maternal Urine and Blood Plasma
Sílvia O. Diaz,Joana Pinto,Gonçalo Graça,Iola F. Duarte,António S. Barros,Eulália Galhano,Cristina Pita,Maria do Céu Almeida,Brian J. Goodfellow,Isabel M. Carreira,Ana M. Gil +10 more
TL;DR: Results show that NMR metabonomics of maternal biofluids enables the noninvasive detection of metabolic changes associated to prenatal disorders, thus unveiling potential disorder biomarkers.
Journal ArticleDOI
Human plasma stability during handling and storage: impact on NMR metabolomics
Joana Pinto,M. Rosário M. Domingues,Eulália Galhano,Cristina Pita,Maria do Céu Almeida,Isabel M. Carreira,Ana M. Gil +6 more
TL;DR: The comparison between heparin and EDTA anti-coagulant collection tubes, the former showed no interference of the polysaccharide, while conserving full spectral information, and the impact of long-term -80 °C storage was found almost negligible.
Journal ArticleDOI
UPLC-MS metabolic profiling of second trimester amniotic fluid and maternal urine and comparison with NMR spectral profiling for the identification of pregnancy disorder biomarkers
Gonçalo Graça,Brian J. Goodfellow,António S. Barros,Sílvia O. Diaz,Iola F. Duarte,Konstantina Spagou,Konstantina Spagou,Kirill Veselkov,Elizabeth J. Want,John C. Lindon,Isabel M. Carreira,Eulália Galhano,Cristina Pita,Ana M. Gil +13 more
TL;DR: The first untargeted UPLC-MS study of 2nd trimester maternal urine and amniotic fluid is reported, to investigate the possible metabolic effects of fetal malformations, gestational diabetes mellitus (GDM) and preterm delivery (PTD).
Journal ArticleDOI
Impact of prenatal disorders on the metabolic profile of second trimester amniotic fluid: a nuclear magnetic resonance metabonomic study.
Gonçalo Graça,Iola F. Duarte,António S. Barros,Brian J. Goodfellow,Sílvia O. Diaz,Joana Pinto,Isabel M. Carreira,Eulália Galhano,Cristina Pita,Ana M. Gil +9 more
TL;DR: Fetal malformations were found to have the highest impact on AF metabolite composition, enabling statistical validation to be achieved by several multivariate analytical tools, and newly found changes suggest possible additional effects on protein and nucleotide sugar biosynthesis.
Journal ArticleDOI
Second Trimester Maternal Urine for the Diagnosis of Trisomy 21 and Prediction of Poor Pregnancy Outcomes
Sílvia O. Diaz,António S. Barros,Brian J. Goodfellow,Iola F. Duarte,Eulália Galhano,Cristina Pita,Maria do Céu Almeida,Isabel M. Carreira,Ana M. Gil +8 more
TL;DR: The value of maternal urine profiling as a complementary means of prenatal diagnostics and early prediction of several poor pregnancy outcomes is demonstrated, for the first time, in this work.