E
Eva Mezey
Researcher at National Institutes of Health
Publications - 209
Citations - 24466
Eva Mezey is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Receptor & Bone marrow. The author has an hindex of 70, co-authored 205 publications receiving 23453 citations. Previous affiliations of Eva Mezey include Semmelweis University.
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Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 production.
Krisztián Németh,Asada Leelahavanichkul,Peter S.T. Yuen,Balázs Mayer,Alissa Parmelee,Kent Doi,Pamela Gehron Robey,Kantima Leelahavanichkul,Beverly H. Koller,Jared M. Brown,Xuzhen Hu,Ivett Jelinek,Robert A. Star,Eva Mezey +13 more
TL;DR: It is suggested that cultured, banked human BMSCs may be effective in treating sepsis in high-risk patient groups because they have been successfully given to humans and can easily be cultured and might be used without human leukocyte antigen matching.
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Turning Blood into Brain: Cells Bearing Neuronal Antigens Generated in Vivo from Bone Marrow
TL;DR: It is shown that, in a strain of mice incapable of developing cells of the myeloid and lymphoid lineages, transplanted adult bone marrow cells migrated into the brain and differentiated into cells that expressed neuron-specific antigens.
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The ubiquitin pathway in Parkinson's disease
Elisabeth Leroy,Rebecca Boyer,Georg Auburger,Barbara Leube,Gudrun Ulm,Eva Mezey,G Harta,Michael J. Brownstein,Sobhanadditya Jonnalagada,Tanya Chernova,Anindya Dehejia,Christian Lavedan,Thomas Gasser,Peter J. Steinbach,Keith D. Wilkinson,Mihael H. Polymeropoulos +15 more
TL;DR: It is shown that in a German family with Parkinson's disease a missense mutation in the ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) gene causes a partial loss of the catalytic activity of this thiol protease, which could lead to aberrations in the proteolytic pathway and aggregation of proteins.
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Hematopoietic cells differentiate into both microglia and macroglia in the brains of adult mice
Martin A. Eglitis,Eva Mezey +1 more
TL;DR: Results indicate that some microglia and astroglia arise from a precursor that is a normal constituent of adult bone marrow, and some bone marrow-derived cells surprisingly expressed the astroglial marker glial fibrillary acidic protein.
Journal ArticleDOI
Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like immunoreactivity, in the central nervous system of the rat and human.
Eva Mezey,Zsuzsanna Tóth,Daniel N. Cortright,Michelle K. Arzubi,James E. Krause,Robert Elde,Athena Guo,Peter M. Blumberg,Arpad Szallasi +8 more
TL;DR: The finding that VR1 is expressed not only in primary sensory neurons but also in several brain nuclei is of great importance in that it places VRs in a much broader perspective than pain perception.