F
F. Rodríguez de Fonseca
Researcher at University of Málaga
Publications - 63
Citations - 6101
F. Rodríguez de Fonseca is an academic researcher from University of Málaga. The author has contributed to research in topics: Cannabinoid & Cannabinoid receptor. The author has an hindex of 35, co-authored 63 publications receiving 5710 citations. Previous affiliations of F. Rodríguez de Fonseca include Carlos III Health Institute & Scripps Research Institute.
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Journal ArticleDOI
Dopamine activation of endogenous cannabinoid signaling in dorsal striatum
Andrea Giuffrida,Loren H. Parsons,Tony M. Kerr,F. Rodríguez de Fonseca,Miguel Navarro,Daniele Piomelli +5 more
TL;DR: Pretreatment with the cannabinoid antagonist SR141716A enhanced the stimulation of motor behavior elicited by systemic administration of quinpirole, suggesting that the endocannabinoid system may act as an inhibitory feedback mechanism countering dopamine-induced facilitation of motor activity.
Journal ArticleDOI
An anorexic lipid mediator regulated by feeding
F. Rodríguez de Fonseca,Miguel Navarro,Raquel Gómez,Leticia Escuredo,Felice Nava,Jin Fu,Eric Murillo-Rodríguez,Andrea Giuffrida,Jesse LoVerme,Silvana Gaetani,Satish Kathuria,Christine M. Gall,Daniele Piomelli +12 more
TL;DR: It is shown that, in rats, food deprivation markedly reduces OEA biosynthesis in the small intestine, and results indicate that OEA is a lipid mediator involved in the peripheral regulation of feeding.
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Increase of extracellular corticotropin-releasing factor-like immunoreactivity levels in the amygdala of awake rats during restraint stress and ethanol withdrawal as measured by microdialysis
Emilio Merlo Pich,Marge T. Lorang,M Yeganeh,F. Rodríguez de Fonseca,Jacob Raber,George F. Koob,Friedbert Weiss +6 more
TL;DR: A progressive increase of CRF-IR levels over time was observed, reaching peak values at 10–12 hr after the onset of withdrawal, and this hypothesis was explored in a series of experiments using intracranial microdialysis to monitorCRF-like immunoreactivity in the extracellular compartment of the rat amygdala.
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Functional Interaction between Opioid and Cannabinoid Receptors in Drug Self-Administration
Miguel Navarro,M. R. A. Carrera,Walter Fratta,Olga Valverde,G Cossu,Liana Fattore,Julie A. Chowen,Ricardo Santiago Gomez,I. del Arco,María Ángeles Villanúa,Rafael Maldonado,George F. Koob,F. Rodríguez de Fonseca +12 more
TL;DR: The present results show the existence of a cross-interaction between opioid and cannabinoid systems in behavioral responses related to addiction and open new strategies for the treatment of opiate dependence.
Journal ArticleDOI
Acute administration of the CB1 cannabinoid receptor antagonist SR 141716A induces anxiety-like responses in the rat.
Miguel Navarro,E. Hernandez,Raúl M. Muñoz,I. del Arco,María Ángeles Villanúa,M. R. A. Carrera,F. Rodríguez de Fonseca +6 more
TL;DR: Results demonstrate that blockade of the endogenous cannabinoid tone might induce anxiety-like responses in rats, and acute administration of SR 141716A induced defensive responses in both anxiety tests.