Fabio Coccolo

TL;DR: AL, ATTRm, and ATTRwt should be considered 3 different cardiac diseases, probably characterized by different pathophysiological substrates and courses.

TL;DR: In the present large cohort of patients with hypertrophic cardiomyopathy, unexplained syncope was a risk factor for sudden death and was maintained throughout all age groups.

TL;DR: To elucidate the genetic basis of PAH further, investigations are needed, including genome scanning for major and minor genes, analysis of genetic profiles of patients for candidate genes likely to modify risk for disease, proteomics, transgenic mice, and altered signal transduction.

TL;DR: Investigation in a large cohort of patients with hypertrophic cardiomyopathy followed up at a cardiology center serving both the pediatric and the adult population found young age at diagnosis, family history of HCM, and greater wall thickness are incremental risk factors for dilated-hypokinetic H CM, which carries an ominous prognosis.

TL;DR: Serum neopterin concentration is associated with the presence of angiographically demonstrated complex lesions in patients with unstable angina and may represent a marker of coronary disease activity.