F
Fan Yang
Researcher at Fudan University
Publications - 3
Citations - 135
Fan Yang is an academic researcher from Fudan University. The author has contributed to research in topics: Serotype & Plasmid. The author has an hindex of 2, co-authored 3 publications receiving 116 citations.
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Journal ArticleDOI
Evidence for Soft Selective Sweeps in the Evolution of Pneumococcal Multidrug Resistance and Vaccine Escape
Nicholas J. Croucher,Nicholas J. Croucher,Claire Chewapreecha,William P. Hanage,Simon R. Harris,Lesley McGee,Mark van der Linden,Jae-Hoon Song,Kwan Soo Ko,Herminia Garcez Lencastre,Herminia Garcez Lencastre,Claudia Turner,Claudia Turner,Fan Yang,Raquel Sá-Leão,Bernard Beall,Keith P. Klugman,Julian Parkhill,Paul Turner,Paul Turner,Stephen D. Bentley,Stephen D. Bentley +21 more
TL;DR: The rapid diversification through homologous recombination seen in the global collection was similarly observed in the absence of vaccination in a set of isolates from the Maela refugee camp in Thailand, a collection that also allowed variation to be observed within carriage through longitudinal sampling, suggesting that some pneumococcal genotypes generate a pool of standing variation that is sufficiently extensive to result in “soft” selective sweeps.
Journal ArticleDOI
Antimicrobial susceptibility and molecular epidemiology of Streptococcus pneumoniae isolated from Shanghai, China.
TL;DR: The findings indicate that the spread of international resistant clones played a predominant role in the emergence and increase of resistance in Shanghai, China, and may be a promising method to prevent the increase in pneumococcal resistance.
Journal ArticleDOI
Promoter variations associated with expression of mcr-1 gene and level of colistin resistance.
TL;DR: Wang et al. as mentioned in this paper characterized the genetic features of mcr-1 gene as well as the role of promoters in gene expression and levels of colistin resistance among clinical isolates of Enterobacteriaceae.