F
Fanqing Chen
Researcher at Lawrence Berkeley National Laboratory
Publications - 2
Citations - 1262
Fanqing Chen is an academic researcher from Lawrence Berkeley National Laboratory. The author has contributed to research in topics: Breast cancer. The author has an hindex of 1, co-authored 2 publications receiving 1216 citations.
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Genomic and transcriptional aberrations linked to breast cancer pathophysiologies.
Koei Chin,Sandy DeVries,Jane Fridlyand,Paul T. Spellman,Ritu Roydasgupta,Wen Lin Kuo,Wen Lin Kuo,Anna Lapuk,Anna Lapuk,Richard M. Neve,Richard M. Neve,Zuwei Qian,Thomas B. Ryder,Fanqing Chen,Heidi S. Feiler,Heidi S. Feiler,Taku Tokuyasu,Chris Kingsley,Shanaz H. Dairkee,Zhenhang Meng,Karen Chew,Daniel Pinkel,Ajay N. Jain,Britt-Marie Ljung,Laura J. Esserman,Donna G. Albertson,Frederic M. Waldman,Joe W. Gray,Joe W. Gray +28 more
TL;DR: It is shown that the recurrent CNAs differ between tumor subtypes defined by expression pattern and that stratification of patients according to outcome can be improved by measuring both expression and copy number, especially high-level amplification.
Genomic andtranscriptional aberrations linked tobreastcancer pathophysiologies
Koei Chin,Sandy DeVries,Jane Fridlyand,Paul T. Spellman,Ritu Roydasgupta,Wen-Lin Kuo,Anna Lapuk,Richard M. Neve,Zuwei Qian,Thomas B. Ryder,Fanqing Chen,Heidi S. Feiler,Taku Tokuyasu,Chris Kingsley,Shanaz Dairkee,Zhenhang Meng,Karen Chew,Daniel Pinkel,Ajay N. Jain,Britt-Marie Ljung,Laura J. Esserman,Donna G. Albertson,Frederic Waldman,Joe W. Gray +23 more
TL;DR: This study explores the roles of genome copy number abnormalities (CNAs) in breast cancer pathophysiology by identifying associations between recurrent CNAs, gene expression, and clinical outcome in a set of aggressively treated early-stage breasttumors.