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Shanaz H. Dairkee
Researcher at California Pacific Medical Center
Publications - 32
Citations - 5907
Shanaz H. Dairkee is an academic researcher from California Pacific Medical Center. The author has contributed to research in topics: Breast cancer & Carcinogenesis. The author has an hindex of 22, co-authored 31 publications receiving 5737 citations. Previous affiliations of Shanaz H. Dairkee include University of California, Berkeley.
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Journal ArticleDOI
High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays
Daniel Pinkel,Daniel Pinkel,Richard Segraves,Damir Sudar,Steven M. Clark,Ian Poole,David Kowbel,Colin Collins,Wen Lin Kuo,Chira Chen,Ye Zhai,Shanaz H. Dairkee,Britt-Marie Ljung,Joe W. Gray,Joe W. Gray,Donna G. Albertson,Donna G. Albertson,Donna G. Albertson +17 more
TL;DR: The implementation of array CGH is demonstrated to be able to measure copy number with high precision in the human genome, and to analyse clinical specimens by obtaining new information on chromosome 20 aberrations in breast cancer.
Journal ArticleDOI
Genomic and transcriptional aberrations linked to breast cancer pathophysiologies.
Koei Chin,Sandy DeVries,Jane Fridlyand,Paul T. Spellman,Ritu Roydasgupta,Wen Lin Kuo,Wen Lin Kuo,Anna Lapuk,Anna Lapuk,Richard M. Neve,Richard M. Neve,Zuwei Qian,Thomas B. Ryder,Fanqing Chen,Heidi S. Feiler,Heidi S. Feiler,Taku Tokuyasu,Chris Kingsley,Shanaz H. Dairkee,Zhenhang Meng,Karen Chew,Daniel Pinkel,Ajay N. Jain,Britt-Marie Ljung,Laura J. Esserman,Donna G. Albertson,Frederic M. Waldman,Joe W. Gray,Joe W. Gray +28 more
TL;DR: It is shown that the recurrent CNAs differ between tumor subtypes defined by expression pattern and that stratification of patients according to outcome can be improved by measuring both expression and copy number, especially high-level amplification.
Journal ArticleDOI
Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene.
Donna G. Albertson,Bauke Ylstra,Richard Segraves,Colin Collins,Shanaz H. Dairkee,David Kowbel,Wen Lin Kuo,Joe W. Gray,Daniel Pinkel +8 more
TL;DR: It is shown here that quantitative measurement of DNA copy number across amplified regions using array comparative genomic hybridization (CGH) may facilitate oncogene identification by providing precise information on the locations of both amplicon boundaries and amplification maxima.
Journal ArticleDOI
Positional cloning of ZNF217 and NABC1: Genes amplified at 20q13.2 and overexpressed in breast carcinoma
Colin Collins,Johanna M. Rommens,David Kowbel,Tony E. Godfrey,Minna Tanner,Soo In Hwang,Daniel Polikoff,Genevieve Nonet,Joanne Cochran,Ken Myambo,Karen E. Jay,Jeff Froula,Thomas Cloutier,Wen Lin Kuo,Paul Yaswen,Shanaz H. Dairkee,Jennifer Giovanola,Gordon B. Hutchinson,Jorma Isola,Olli Kallioniemi,Mike Palazzolo,Christopher Martin,Cheryl L. Ericsson,Daniel Pinkel,Daniel Pinkel,Donna G. Albertson,Donna G. Albertson,Wu Bo Li,Joe W. Gray,Joe W. Gray +29 more
TL;DR: The molecular cloning of an approximately 1-Mb region of recurrent amplification at 20q13.2 in breast cancer and other tumors and the delineation of a 260-kb common region of amplification are reported.
Journal ArticleDOI
Enhanced NFκB and AP-1 transcriptional activity associated with antiestrogen resistant breast cancer
Yamei Zhou,Christina Yau,Joe W. Gray,Karen Chew,Shanaz H. Dairkee,Dan H. Moore,Dan H. Moore,Urs Eppenberger,Serenella Eppenberger-Castori,Christopher C. Benz,Christopher C. Benz +10 more
TL;DR: Doses of parthenolide and bortezomib capable of sensitizing the two endocrine resistant breast cancer models to tamoxifen were capable of suppressing NFκB and AP-1 regulated gene expression in combination with tamoxIFen and also increased ER recruitment of the transcriptional co-repressor, NCoR.