F
Feng-Nien Ko
Researcher at National Taiwan University
Publications - 70
Citations - 3734
Feng-Nien Ko is an academic researcher from National Taiwan University. The author has contributed to research in topics: Platelet & Thromboxane B2. The author has an hindex of 35, co-authored 69 publications receiving 3619 citations. Previous affiliations of Feng-Nien Ko include Tamkang University & China Medical University (Taiwan).
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YC-1, a novel activator of platelet guanylate cyclase.
TL;DR: The data indicate that YC-1 is a direct soluble guanylate cyclase activator in rabbit platelets and may also possess antithrombotic potential in vivo.
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YC-1 inhibited human platelet aggregation through NO-independent activation of soluble guanylate cyclase.
TL;DR: The results would suggest that YC‐1 activates sGC of human platelets by a NO‐independent mechanism, and exerts its antiplatelet effects through the sGC/cyclic GMP pathway.
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Two antiplatelet agents from Magnolia officinalis.
Che-Ming Teng,Chien Chih Chen,Feng-Nien Ko,Lih-Gen Lee,Tur-Fu Huang,Yuh-Pan Chen,Hong-Yen Hsu +6 more
TL;DR: It is concluded that the antiplatelet effect of magnolol and honokiol is due to an inhibitory effect on thromboxane formation and also an inhibition of intracellular calcium mobilization.
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Antiplatelet components in Panax ginseng.
TL;DR: Panaxynol and ginsenosides Ro, Rg1, and Rg2 were found to be the main antiplatelet components in the diethyl ether and 1-butanol fractions, respectively, during the activity-guided fractionation of Panax ginseng.
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Coumarins and antiplatelet aggregation constituents from Formosan Peucedanum japonicum.
Ih-Sheng Chen,Chin-Teng Chang,Wine-Show Sheen,Che-Ming Teng,Ian-Lih Tsai,Chang-Yih Duh,Feng-Nien Ko +6 more
TL;DR: Seven compounds, eugenin, (-)-selinidin, (+)-pteryxin, imperatorin, bergapten, cnidilin and (+)-visamminol, show strong antiplatelet aggregation activity in vitro.