F
Fernanda M. Frank
Researcher at University of Buenos Aires
Publications - 43
Citations - 1333
Fernanda M. Frank is an academic researcher from University of Buenos Aires. The author has contributed to research in topics: Trypanosoma cruzi & Antigen. The author has an hindex of 22, co-authored 42 publications receiving 1214 citations. Previous affiliations of Fernanda M. Frank include National Scientific and Technical Research Council & National University of Cordoba.
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Journal ArticleDOI
Trypanocidal and Leishmanicidal Activities of Sesquiterpene Lactones from Ambrosia tenuifolia Sprengel (Asteraceae)
Valeria P. Sülsen,Fernanda M. Frank,Silvia I. Cazorla,Claudia Anesini,Emilio L. Malchiodi,Blanca Freixa,Roser Vila,Liliana Muschietti,Virginia Martino +8 more
TL;DR: The results shown herein suggest that psilostachyin and peruvin could be considered potential candidates for the development of new antiprotozoal agents against Chagas' disease and leishmaniasis.
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Oral Vaccination with Salmonella enterica as a Cruzipain-DNA Delivery System Confers Protective Immunity against Trypanosoma cruzi
Silvia I. Cazorla,Pablo D. Becker,Fernanda M. Frank,Thomas Ebensen,M.J. Sartori,Ricardo S. Corral,Emilio L. Malchiodi,Carlos A. Guzmán +7 more
TL;DR: It is indicated that Salmonella-mediated delivery of Cz-DNA by itself promotes the elicitation of an immune response that controls T. cruzi infection, thereby reducing parasite loads and subsequent damage to muscle tissues.
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Characterization of human infection by Leishmania spp. in the Northwest of Argentina: immune response, double infection with Trypanosoma cruzi and species of Leishmania involved.
Fernanda M. Frank,Marisa M. Fernández,Néstor J. Taranto,Silvana P. Cajal,Ricardo A. Margni,Eliane Dias de Castro,V. Thomaz-Soccol,Emilio L. Malchiodi +7 more
TL;DR: Results indicate that the strong immune response against T. cruzi gave no protection to Leishmania, in spite of the serological cross-reaction between these parasites, and it is shown that more than 40% of the patients would be misdiagnosed as chagasic if complex antigens, as epimastigotes or soluble fraction from epimastsigotes, were used in IFA or ELISA.
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Trypanocidal and leishmanicidal activities of flavonoids from Argentine medicinal plants.
Valeria P. Sülsen,Silvia I. Cazorla,Fernanda M. Frank,Flavia Redko,Claudia Anesini,Jorge D. Coussio,Emilio L. Malchiodi,Virginia Martino,Liliana Muschietti +8 more
TL;DR: Hispidulin was more active than santin on promastigotes of Leishmania mexicana and no cytotoxic activity was observed on lymphoid cells, making hispidulin and s Santin potential lead compounds for the development of new natural drugs.
Journal ArticleDOI
Vaccination approaches against Trypanosoma cruzi infection
TL;DR: The recent advances in vaccine research and the development of the major antigen candidates, including cruzipain, trans-sialidase, amastigote surface protein, paraflagellar rod protein, among others are reviewed.