F
Flavia A.M. de Sousa
Researcher at Federal University of Ceará
Publications - 3
Citations - 170
Flavia A.M. de Sousa is an academic researcher from Federal University of Ceará. The author has contributed to research in topics: Lectin & Dioclea guianensis. The author has an hindex of 3, co-authored 3 publications receiving 169 citations.
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Journal ArticleDOI
Diocleinae Lectins Are a Group of Proteins with Conserved Binding Sites for the Core Trimannoside of Asparagine-linked Oligosaccharides and Differential Specificities for Complex Carbohydrates*
Tarun K. Dam,Benildo Sousa Cavada,Thalles B. Grangeiro,Cláudia F. Santos,Flavia A.M. de Sousa,Stefan Oscarson,C. Fred Brewer +6 more
TL;DR: The ability of the lectins to induce histamine release from rat peritoneal mast cells is shown to correlate with the relative affinities of the proteins for the biantennary carbohydrate.
Journal ArticleDOI
Purification and characterization of a lectin from seeds of Vatairea macrocarpa duke
Benildo Sousa Cavada,Cláudia F. Santos,Thalles B. Grangeiro,Edson P. Nunes,Patricia V.P. Sales,Ronaldo L. Ramos,Flavia A.M. de Sousa,Clebia Vieira Crisostomo,Juan J. Calvete +8 more
TL;DR: A lectin from Vatairea macrocarpa Duke seeds (VML) was isolated using affinity chromatography on a guar gum column and size-exclusion chromatography indicated that VML is predominantly a dimeric protein, although tetramers and larger aggregates were also present.
Journal ArticleDOI
Thermodynamic binding studies of lectins from the diocleinae subtribe to deoxy analogs of the core trimannoside of asparagine-linked oligosaccharides.
Tarun K. Dam,Benildo Sousa Cavada,Thalles B. Grangeiro,Cláudia F. Santos,Vania M. Ceccatto,Flavia A.M. de Sousa,Stefan Oscarson,C. Fred Brewer +7 more
TL;DR: Isothermal titration microcalorimetry is used to determine the binding thermodynamics of the above lectins, including a new lectin from Canavalia grandiflora, to a complete series of monodeoxy analogs of the core trimannoside, showing differences in the magnitude of the thermodynamic binding parameters of the lectins.