F
Florence Danede
Researcher at university of lille
Publications - 90
Citations - 2161
Florence Danede is an academic researcher from university of lille. The author has contributed to research in topics: Differential scanning calorimetry & Amorphous solid. The author has an hindex of 25, co-authored 77 publications receiving 1835 citations. Previous affiliations of Florence Danede include Lille University of Science and Technology & Centre national de la recherche scientifique.
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Evidence for a New Crystalline Phase of Racemic Ibuprofen
TL;DR: It is established, for the first time, that Ibuprofen can exist under two different crystalline phases which constitute a monotropic system, the new form being metastable.
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Solid state NMR and DSC methods for quantifying the amorphous content in solid dosage forms: an application to ball-milling of trehalose
TL;DR: The results reveal a close correlation between the imposed compositions of the physical mixtures and those determined by NMR and DSC, indicating that both are useful and accurate methods for compositional characterization of powders.
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A new protocol to determine the solubility of drugs into polymer matrixes.
TL;DR: A new protocol to determine faster the solubility of drugs into polymer matrixes based on the fact that the equilibrium saturated states are reached by demixing of supersaturated amorphous solid solutions and not by dissolution of crystalline drug into theAmorphous polymer matrix as for usual methods.
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Direct crystal to glass transformation of trehalose induced by ball milling
TL;DR: In this article, structural and thermodynamic changes in the organic molecular crystal of trehalose upon high energy ball milling have been studied by X-ray diffraction and by differential scanning calorimetry.
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Does PLGA microparticle swelling control drug release? New insight based on single particle swelling studies
TL;DR: The onset of the third drug release phase from the PLGA microparticles might be explained as follows: once the macromolecules are sufficiently short, substantial amounts of water penetrate into the system, significantly increasing the mobility of the drug within the microparticle and resulting in increased drug release rates.