F
Florian B. Otto
Researcher at University of Göttingen
Publications - 3
Citations - 56
Florian B. Otto is an academic researcher from University of Göttingen. The author has contributed to research in topics: Microautophagy & Nucleophagy. The author has an hindex of 3, co-authored 3 publications receiving 27 citations.
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Journal ArticleDOI
Mechanistic dissection of macro- and micronucleophagy.
Florian B. Otto,Michael Thumm +1 more
TL;DR: This study details the involvement of Atg8 in both macronucleophagy and PMN and identifies Atg39 as the general cargo receptor for nucleophagic processes and suggests a role for Atg 39 in micronuclephagy.
Journal ArticleDOI
Atg21 organizes Atg8 lipidation at the contact of the vacuole with the phagophore.
Lena Munzel,Piotr Neumann,Florian B. Otto,Roswitha Krick,Janina Metje-Sprink,Benjamin Kroppen,Narain Karedla,Jörg Enderlein,Michael Meinecke,Ralf Ficner,Michael Thumm +10 more
TL;DR: A specialized vacuolar subdomain at the VICS, typical of organellar contact sites, where the membrane protein Vph1 was excluded, while Vac8 was concentrated, was identified and support a specializedOrganellar contact involved in controlling phagophore elongation.
Journal ArticleDOI
Nucleophagy-Implications for Microautophagy and Health.
Florian B. Otto,Michael Thumm +1 more
TL;DR: Nucleophagy, the selective subtype of autophagy that targets nuclear material for autophagic degradation, was not only shown to be a model system for the study of selective macroautophagosome biogenesis, but also for elucidating the role of the core Autophagic machinery within microautophagy.