50 Years of Image Analysis

Hydrogels for biomedical applications.

Sustainable solvents are a topic of growing interest in both the research community and the chemical industry due to a growing awareness of the impact of solvents on pollution, energy usage, and contributions to air quality and climate change. Solvent losses represent a major portion of organic pollution, and solvent removal represents a large proportion of process energy consumption. To counter these issues, a range of greener or more sustainable solvents have been proposed and developed over the past three decades. Much of the focus has been on the environmental credentials of the solvent itself, although how a substance is deployed is as important to sustainability as what it is made from. In this Review, we consider several aspects of the most prominent sustainable organic solvents in use today, ionic liquids, deep eutectic solvents, supercritical fluids, switchable solvents, liquid polymers, and renewable solvents. We examine not only the performance of each class of solvent within the context of the...

Green and Sustainable Solvents in Chemical Processes

https://mostwiedzy.pl/pl/publication/download/1/a-new-tool-for-the-evaluation-of-the-analytical-procedure-green-analytical-procedure-index_24146.pdf

A new tool for the evaluation of the analytical procedure: Green Analytical Procedure Index.

There is great need for stand-alone luminescence-based chemosensors that exemplify selectivity, sensitivity, and applicability and that overcome the challenges that arise from complex, real-world media. Discussed herein are recent developments toward these goals in the field of supramolecular luminescent chemosensors, including macrocycles, polymers, and nanomaterials. Specific focus is placed on the development of new macrocycle hosts since 2010, coupled with considerations of the underlying principles of supramolecular chemistry as well as analytes of interest and common luminophores. State-of-the-art developments in the fields of polymer and nanomaterial sensors are also examined, and some remaining unsolved challenges in the area of chemosensors are discussed.

/pdf/supramolecular-luminescent-sensors-1rs45r4um4.pdf

Supramolecular Luminescent Sensors

Enantioselective Chitosan-based Racemic Ketoprofen Imprinted Polymer: Chiral Recognition and Resolution Study

Ibandronate is a non-chromophoric bisphosphonate drug containing a tertiary amine group, which does not easily react with chromophoric and chromogenic agents. The current report describes the devel...

Indirect Spectrophotometric Determination of Ibandronate in Pharmaceutical Formulations via Ligand Exchange

Physicochemical and electrochemical methods for determination of critical micelle concentrations of surfactants: a comprehensive review

Ibandronate sodium monohydrate is a highly polar aliphatic compound that belongs to the bisphosphonate class, a widely used bone resorption inhibitor. The aliphatic nature of ibandronate precludes direct photometric detection and its high polarity urged analysts to use ion-pairing agents in the mobile phase to promote retention in reversed-phase columns. In this work, a reversed-phase method for determination of ibandronate sodium monohydrate in pharmaceutical tablets is introduced by employing an online postcolumn ligand exchange reaction to enable photometric detection. The method offers for the first time the ability to separate the drug from its well-known impurities on conventional reversed-phase columns. The detection reaction depends on the ability of ibandronate and its degradation products to displace salicylate in the iron(III) salicylate complex, forming various colorless iron (III) complexes and showing a negative chromatographic signal for ibandronate and its degradants at λmax = 525 nm. The chromatographic separation was achieved using a Hypersil BDS C8 column (5 µm particle size, 150 mm × 4.6 mm i.d.) and a mobile phase consisting of a mixture of aqueous formate buffer pH 3 (pH 3, 5 mM) and methanol in a ratio of 80:20% (v/v), delivered at a flow rate of 0.8 mL/min. The postcolumn iron(III) salicylate reagent was prepared at 250 µM in aqueous formate buffer, delivered using a syringe pump at a flow rate of 0.5 mL/min. The proposed method was validated as per the guidelines of the International Conference on Harmonization Q2(R1) and was found linear over the range 40–120 µg/mL (r = 0.9995) with a limit of detection of 3.19 µg/mL. Compared to currently reported methods, the proposed method is considerably simpler, faster, cheaper, and adequately sensitive and makes use of the most popular LC detectors.

Fotouh R. Mansour

Papers

Enantioselective Chitosan-based Racemic Ketoprofen Imprinted Polymer: Chiral Recognition and Resolution Study

Indirect Spectrophotometric Determination of Ibandronate in Pharmaceutical Formulations via Ligand Exchange

Physicochemical and electrochemical methods for determination of critical micelle concentrations of surfactants: a comprehensive review

Online Postcolumn Indirect Detection for Determination of Ibandronate in Pharmaceutical Tablets by HPLC/DAD

A highly sensitive switch-on spectrofluorometric method for determination of ascorbic acid using a selective eco-friendly approach