Francesca Zimetti

TL;DR: It is concluded that apoA-I inhibits atherosclerosis by promoting both macrophage reverse cholesterol transport and HDL antiinflammatory function, and that these anti-atherogenic functions of apo-I are largely independent of the plasma level of HDL-C in this mouse model.

TL;DR: Although some polyphenols might improve specific markers of cardiovascular risk and cognitive status, many inconsistent data are present in literature, therefore, definitive recommendations for the use of these compounds in the prevention of cardiovascular disease and cognitive decline are currently not applicable.

TL;DR: In this paper, the capacity of high-density lipoproteins (HDL) to promote cell cholesterol efflux is investigated in rheumatoid arthritis (RA) and systemic lupus erythemathosus (SLE) patients.

TL;DR: Probucol is an effective inhibitor of ABCA1-mediated cholesterol efflux without influencing scavenger receptor class B type I–mediated efflux, which may in part explain the reported in vivo high-density lipoprotein–lowering action of probucol.

TL;DR: The results indicate that chymase treatment of HDL3 specifically impairs the ABCA1-dependent pathway without influencing either aqueous or SR-BI-facilitated diffusion and that this effect is caused by depletion of lipid-poor pre-β-migrating particles in HDL3.