F
Francesco M. Marincola
Researcher at National Institutes of Health
Publications - 473
Citations - 41473
Francesco M. Marincola is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Immune system & Antigen. The author has an hindex of 94, co-authored 462 publications receiving 38129 citations. Previous affiliations of Francesco M. Marincola include Society for Immunotherapy of Cancer & Virginia Commonwealth University.
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Journal ArticleDOI
Correlates Between Host and Viral Transcriptional Program Associated with Different Oncolytic Vaccinia Virus Isolates
Jennifer Reinboth,Maria Libera Ascierto,Nanhai G. Chen,Qian Zhang,Yong A. Yu,Richard J. Aguilar,Rafael Carretero,Andrea Worschech,Yingdong Zhao,Ena Wang,Francesco M. Marincola,Aladar A. Szalay +11 more
TL;DR: The characterization of human target genes that influence viral replication could help answer the question of host cell permissiveness to oncolytic virotherapy and provide important information for the development of novel recombinant vaccinia viruses with improved features to enhance replication rate and hence trigger therapeutic outcome.
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Contextual Reprogramming of CAR-T Cells for Treatment of HER2+ Cancers
Zhifen Yang,Lingyu Li,Ahu Turkoz,Pohan Chen,Rona Harari-Steinfeld,Alper Kearney,Dharmesh Patel,Vitaly Balan,Maggie Bobbin,Hana Choi,Ofir Stefanson,Damla Inel,Veena Vinod,Alessandra Cesano,Bing Wang,Kyung-Ho Roh,Lei S. Qi,Francesco M. Marincola +17 more
TL;DR: The conditional, non-gene editing and reversible suppression promotes CAR-T cells resilience to checkpoint inhibition, and their persistence and effectiveness against HER2-expressing cancer xenografts.
Journal Article
How to analyze ex vivo T-cell responses in cancer patients.
TL;DR: The most important techniques for specific T-cell analyses including cytokine-based functional assays, HLA class I/epitope tetrameric complexes, and PCR-based methods are reviewed and compared.
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Future of immunotherapy: a call for comparative immunology.
TL;DR: The strategy to identify common immunologic themes relevant to human pathology include comparisons of immunologic events necessary for the occurrence of distinct immune-mediated diseases, and it is argued that this is most effectively studied following a bottom-up, inductive approach using high-throughput technology.
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AAAS joins the Translational Medicine family
TL;DR: The AAAS has announced the launch of Science Translational Medicine, which will provide another valuable venue for the rapid and broad dissemination of important articles in the field and contribute to enhancing the effectiveness of translational medicine overall.