F
Francesco Tomasello
Researcher at University of Messina
Publications - 292
Citations - 7466
Francesco Tomasello is an academic researcher from University of Messina. The author has contributed to research in topics: Meningioma & Subarachnoid hemorrhage. The author has an hindex of 44, co-authored 291 publications receiving 6926 citations. Previous affiliations of Francesco Tomasello include First Faculty of Medicine, Charles University in Prague & University of Naples Federico II.
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Journal ArticleDOI
Type I IFN signaling is crucial for host resistance against different species of pathogenic bacteria
Giuseppe Mancuso,Angelina Midiri,Carmelo Biondo,Concetta Beninati,Sebastiana Zummo,Roberta Galbo,Francesco Tomasello,Maria Elsa Gambuzza,Giancarlo Macrì,Alessia Ruggeri,Tomas Leanderson,Giuseppe Teti +11 more
TL;DR: It is shown in this study that IFN-αβ signaling is crucial for host defenses against different bacteria, including group B streptococci (GBS), pneumococci, and Escherichia coli, and Animals lacking bothIFN- αβR and IFn-γR displayed additive lethality, suggesting that the two IFN types have complementary and nonredundant roles in host defenses.
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miR-21 and 221 upregulation and miR-181b downregulation in human grade II–IV astrocytic tumors
Alfredo Conti,M'hammed Aguennouz,Domenico La Torre,Chiara Tomasello,Salvatore Cardali,Filippo Flavio Angileri,Francesca Maio,Annamaria Cama,Antonino Germanò,Giuseppe Vita,Francesco Tomasello +10 more
TL;DR: The different expression pattern observed in tumors at different stages of malignancy is probably dependent on the cell-specific repertoire of target genes of tumors sharing different molecular pathways activity and suggests miRNAs may have also a place in diagnosis and staging of brain tumors.
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Does early decompression improve neurological outcome of spinal cord injured patients? Appraisal of the literature using a meta-analytical approach
TL;DR: Investigating whether neurological outcome is improved in traumatic spinal cord-injured patients who had surgery within 24 h as compared with those who had late surgery or conservative treatment found early decompression resulted in better outcome.
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Beneficial effects of systemic administration of recombinant human erythropoietin in rabbits subjected to subarachnoid hemorrhage
Giovanni Grasso,Michele Buemi,Concetta Alafaci,Alessandra Sfacteria,Marcello Passalacqua,Alessio Sturiale,Gioacchino Calapai,Gionata De Vico,Giuseppe Piedimonte,Francesco M. Salpietro,Francesco Tomasello +10 more
TL;DR: Observations suggest that r-Hu-EPO may provide an effective treatment to reduce the post-SAH morbidity.
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MyD88 and TLR2, but not TLR4, are required for host defense against Cryptococcus neoformans.
Carmelo Biondo,Angelina Midiri,Luciano Messina,Francesco Tomasello,Gabriella Garufi,Maria Rosaria Catania,Mauro Bombaci,Concetta Beninati,Giuseppe Teti,Giuseppe Mancuso +9 more
TL;DR: It is indicated that TLR2 and MyD88, but not TLR4, critically contribute to anti‐cryptococcal defenses through the induction of increased TNF‐α, IL‐12 and IFN‐γ expression.