F
Francine Goltzene
Publications - 1
Citations - 153
Francine Goltzene is an academic researcher. The author has contributed to research in topics: Nuclear DNA & Transfer RNA. The author has an hindex of 1, co-authored 1 publications receiving 143 citations.
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Nuclear DNA-encoded tRNAs targeted into mitochondria can rescue a mitochondrial DNA mutation associated with the MERRF syndrome in cultured human cells
Olga Kolesnikova,Nina Entelis,Clarisse Jacquin-Becker,Francine Goltzene,Zofia M.A. Chrzanowska-Lightowlers,Robert N. Lightowlers,Robert P. Martin,Ivan Tarassov +7 more
TL;DR: These findings prove for the first time the functionality of imported tRNAs in human mitochondria in vivo and highlight the potential for exploiting the RNA import pathway to treat patients with mtDNA diseases.