F
Francisco Villarreal
Researcher at University of California, San Diego
Publications - 192
Citations - 8422
Francisco Villarreal is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Laser & Medicine. The author has an hindex of 48, co-authored 178 publications receiving 7475 citations. Previous affiliations of Francisco Villarreal include University of San Diego & University of California, Los Angeles.
Papers
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Journal ArticleDOI
The pathogenesis of myocardial fibrosis in the setting of diabetic cardiomyopathy
Juan Asbun,Francisco Villarreal +1 more
TL;DR: The state of knowledge on the effects that diabetes-like conditions exert on the cells responsible for ECM production is reviewed as well as relevant experimental and clinical data.
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Role of mechanical factors in modulating cardiac fibroblast function and extracellular matrix synthesis
TL;DR: The development of in vitro strain apparatuses has allowed scientists to investigate the effects of mechanical stimuli on cardiac fibroblast function and the roles that mechanical stimuli play in excess deposition of myocardial ECM are investigated.
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Identification of functional angiotensin II receptors on rat cardiac fibroblasts.
TL;DR: Results from this study indicate that neonatal and adult rat cardiac fibroblasts in culture express AT, receptors for Ang II, and suggest that Ang II might have important regulatory roles over cardiac Fibroblast function under normal and pathological conditions.
Journal ArticleDOI
Tetracyclines: a pleitropic family of compounds with promising therapeutic properties. Review of the literature
Michael O. Griffin,Eduardo Fricovsky,Guillermo Ceballos,Guillermo Ceballos,Francisco Villarreal +4 more
TL;DR: A summary of tetracycline's multiple mechanisms of action is provided and while using the effects on the heart as an example, their potential to benefit patients suffering from various pathologies such as cancer, Rosacea, and Parkinson's disease is noted.
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Cardiac hypertrophy-induced changes in mRNA levels for TGF-beta 1, fibronectin, and collagen.
TL;DR: Findings indicate that, with myocardial hypertrophy, mRNAs for fibronectin are increased as early as 1 day after banding, which may allow for an initial increase in the production of fibronsectin followed by the deposition of collagen.