F
Francoise Perdreau-Remington
Researcher at University of California, San Francisco
Publications - 50
Citations - 7564
Francoise Perdreau-Remington is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Methicillin-resistant Staphylococcus aureus & Staphylococcal infections. The author has an hindex of 32, co-authored 50 publications receiving 7270 citations. Previous affiliations of Francoise Perdreau-Remington include University of Cologne & San Francisco General Hospital.
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Journal ArticleDOI
Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus
Binh An Diep,Binh An Diep,Steven R. Gill,Richard F. Chang,Richard F. Chang,Tiffany HaiVan Phan,Jason H. Chen,Matthew G. Davidson,Felice Lin,Jessica Lin,Heather A. Carleton,Emmanuel F. Mongodin,George F. Sensabaugh,Francoise Perdreau-Remington +13 more
TL;DR: The most striking feature of the USA300 genome is the horizontal acquisition of a novel mobile genetic element that encodes an arginine deiminase pathway and an oligopeptide permease system that could contribute to growth and survival of USA300.
Journal ArticleDOI
Necrotizing Fasciitis Caused by Community-Associated Methicillin-Resistant Staphylococcus aureus in Los Angeles
Loren G. Miller,Francoise Perdreau-Remington,Gunter Rieg,Sheherbano Mehdi,Josh Perlroth,Arnold S. Bayer,Angela W. Tang,Tieu O. Phung,Brad Spellberg +8 more
TL;DR: In areas in which community-associated MRSA infection is endemic, empirical treatment of suspected necrotizing fasciitis should include antibiotics predictably active against this pathogen.
Journal ArticleDOI
High prevalence of methicillin-resistant Staphylococcus aureus in emergency department skin and soft tissue infections
Bradley W. Frazee,Jeremy Lynn,Edwin D. Charlebois,Larry Lambert,Derrick Lowery,Francoise Perdreau-Remington +5 more
TL;DR: In this urban ED population, MRSA is a major pathogen in skin and soft tissue infections and should be considered when empiric antibiotic therapy is selected for such infections.
Journal ArticleDOI
The Arginine Catabolic Mobile Element and Staphylococcal Chromosomal Cassette mec Linkage: Convergence of Virulence and Resistance in the USA300 Clone of Methicillin-Resistant Staphylococcus aureus
Binh An Diep,Binh An Diep,Gregory G. Stone,Li Basuino,Christopher J. Graber,Alita A. Miller,Shelley G. des Etages,Alison E. Jones,Amy M. Palazzolo-Ballance,Francoise Perdreau-Remington,George F. Sensabaugh,Frank R. DeLeo,Henry F. Chambers +12 more
TL;DR: It is found that deletion of type IV SCCmec did not affect competitive fitness, whereas deletion of ACME significantly attenuated the pathogenicity or fitness of USA300, consistent with a model in which ACME enhances growth and survival of America300, allowing for genetic "hitchhiking" of SCCMec.
Journal ArticleDOI
Emergence of Multidrug-Resistant, Community-Associated, Methicillin-Resistant Staphylococcus aureus Clone USA300 in Men Who Have Sex with Men
Binh An Diep,Henry F. Chambers,Christopher J. Graber,John D. Szumowski,Loren G. Miller,Linda L. Han,Jason H. Chen,Felice Lin,Jessica Lin,Tiffany HaiVan Phan,Heather A. Carleton,Linda K. McDougal,Fred C. Tenover,Daniel E. Cohen,Kenneth H. Mayer,George F. Sensabaugh,Francoise Perdreau-Remington +16 more
TL;DR: The authors demonstrate that the incidence of multidrug-resistant USA300 MRSA is highest in the areas of San Francisco where more male same-sex couples reside, and factors associated with its spread in this high-risk population are described.