F
Frank Caruso
Researcher at University of Melbourne
Publications - 676
Citations - 68648
Frank Caruso is an academic researcher from University of Melbourne. The author has contributed to research in topics: Polyelectrolyte & Nanoparticle. The author has an hindex of 131, co-authored 641 publications receiving 61748 citations. Previous affiliations of Frank Caruso include Commonwealth Scientific and Industrial Research Organisation & University of Rome Tor Vergata.
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Journal ArticleDOI
Achieving HIV-1 Control through RNA-Directed Gene Regulation
Vera Klemm,Jye Mitchell,Christina Cortez-Jugo,Francesca Cavalieri,Geoff Symonds,Frank Caruso,Anthony D. Kelleher,Chantelle L Ahlenstiel +7 more
TL;DR: An overview of the silencing pathways, the current RNAi technologies being developed for HIV-1 gene therapy, current clinical trials, and the challenges faced in progressing these treatments into clinical trials are provided.
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Interactions between circulating nanoengineered polymer particles and extracellular matrix components in vitro.
Julia A. Braunger,Mattias Björnmalm,Nathan A. Isles,Jiwei Cui,Timothy M A Henderson,Andrea J. O'Connor,Frank Caruso +6 more
TL;DR: A system for investigating the interactions between circulating polymer particles and ECM components in vitro using a commercially available flow-based device is presented and it is shown that scaffold-effects (porosity and surface chemistry) impact on circulation time in vitro.
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Nanoengineering multifunctional hybrid interfaces using adhesive glycogen nanoparticles
Pietro Pacchin Tomanin,Jiajing Zhou,Alessia Amodio,Rita Cimino,Agata Glab,Francesca Cavalieri,Francesca Cavalieri,Frank Caruso +7 more
TL;DR: The engineering of multifunctional hybrid films by assembling adhesive biological nanoparticles composed of lipoate-conjugated phytoglycogen (L-PG) showed negligible cytotoxicity and moderate stability under different conditions but displayed enzyme-mediated degradability.
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Advancing Research Using Action Cameras
TL;DR: Caruso et al. as discussed by the authors explored the use of first-person action cameras (e.g., GoPro cameras) to record experiments, methods, and equipment procedures in their laboratory and also recorded the training sessions for their equipment and instruments, their laboratory inductions, and (bio)safety procedures to complement their conventional training.
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Unravelling "off-target" effects of redox-active polymers and polymer multilayered capsules in prostate cancer cells
Giovanni Luca Beretta,Marco Folini,Francesca Cavalieri,Francesca Cavalieri,Yan Yan,Enrico Fresch,Subramanian Kaliappan,Christoph Hasenöhrl,Joseph J. Richardson,Stella Tinelli,Andreas Fery,Frank Caruso,Nadia Zaffaroni +12 more
TL;DR: Exposure to redox-active polymer and thin multilayer capsules and the conversion of the carboxyl groups of PMA(SH) into the neutral amides of poly(hydroxypropylmetacrylamide) (pHPMA(SH)) nullified the off-target effects and cytotoxicity in tested cell lines.