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Frank Caruso

Researcher at University of Melbourne

Publications -  676
Citations -  68648

Frank Caruso is an academic researcher from University of Melbourne. The author has contributed to research in topics: Polyelectrolyte & Nanoparticle. The author has an hindex of 131, co-authored 641 publications receiving 61748 citations. Previous affiliations of Frank Caruso include Commonwealth Scientific and Industrial Research Organisation & University of Rome Tor Vergata.

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Probing cell internalisation mechanics with polymer capsules

TL;DR: It was found that human monocyte-derived macrophage THP-1 cells exerted up to approximately 360 kPa on the capsules during internalisation.
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Tuning the Properties of Polymer Capsules for Cellular Interactions.

TL;DR: The preparation of various polymer capsules with different compositions and properties via atom transfer radical polymerization mediated continuous assembly of polymers (CAPATRP) is reported, where the cellular interactions of these capsules, particularly fouling and specific targeting, are examined by flow cytometry and deconvolution microscopy.
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Engineering Enzyme-Cleavable Hybrid Click Capsules with a pH-Sheddable Coating for Intracellular Degradation

TL;DR: The engineering of layer-by-layer (LbL) hybrid click capsules that are responsive to biological stimuli is reported that comprise a pH-sheddable, non cross-linked outer coating that protects enzyme-cleavable inner layers.
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Photocontrolled Cargo Release from Dual Cross-Linked Polymer Particles.

TL;DR: In this article, the dual cross-linked particles (DCPs) were efficiently infiltrated by the biomacromolecule dextran (molecular weight up to 500 kDa) to provide high loadings.
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Influence of Poly(ethylene glycol) Molecular Architecture on Particle Assembly and Ex Vivo Particle-Immune Cell Interactions in Human Blood

TL;DR: In this paper, a mesoporous silica (MS) templating method was used to generate PEG particles with a denser, stiffer structure, with increasing elastic modulus from 1.5 to 14.9 kPa, inducing an increasing level of immune cell association with monocytes.