F
Frank Müller
Researcher at University of Hamburg
Publications - 27
Citations - 822
Frank Müller is an academic researcher from University of Hamburg. The author has contributed to research in topics: Hearing loss & Phonation. The author has an hindex of 13, co-authored 27 publications receiving 738 citations. Previous affiliations of Frank Müller include University of Freiburg.
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Journal ArticleDOI
Glucosylceramide Synthases, a Gene Family Responsible for the Biosynthesis of Glucosphingolipids in Animals, Plants, and Fungi
Martina Leipelt,Dirk Warnecke,Ulrich Zähringer,Claudia Ott,Frank Müller,Bernhard Hube,Ernst Heinz +6 more
TL;DR: A systematic functional analysis of a glycosyltransferase gene family with members of animal, plant, fungal, and bacterial origin found five novel glucosylceramide synthase genes were identified from the plant Gossypium arboreum, the nematode Caenorhabditis elegans, and the fungi Magnaporthe grisea, Candida albicans, and P. pastoris.
Journal ArticleDOI
Cloning and functional expression of UGT genes encoding sterol glucosyltransferases from Saccharomyces cerevisiae, Candida albicans, Pichia pastoris, and Dictyostelium discoideum.
Dirk Warnecke,Ralf Erdmann,Annette Fahl,Bernhard Hube,Frank Müller,Thorsten K. Zank,Ulrich Zähringer,Ernst Heinz +7 more
TL;DR: In vitro enzyme assays with cell-free extracts of the transgenic E. coli strains showed that the genes encode UDP-glucose:sterol glucosyltransferases which can use different sterols such as cholesterol, sitosterol, and ergosterol as sugar acceptors and prove that sterol glucOSide synthesis is an inherent feature of eukaryotic microorganisms.
Journal ArticleDOI
Peroxisome degradation requires catalytically active sterol glucosyltransferase with a GRAM domain
Masahide Oku,Dirk Warnecke,Takeshi Noda,Frank Müller,Frank Müller,Ernst Heinz,Hiroyuki Mukaiyama,Nobuo Kato,Yasuyoshi Sakai,Yasuyoshi Sakai +9 more
TL;DR: It is described herein that sterol glucosyltransferase (Ugt51/Paz4) is essential for pexophagy (peroxisome degradation), but not for macroautophagy in the methylotrophic yeast Pichia pastoris, suggesting that SG synthesis is required for this process.
Journal ArticleDOI
Structure of a gene encoding heat-shock protein HSP70 from the unicellular alga Chlamydomonas reinhardtii.
TL;DR: The structure of a gene encoding a 70-kDa heat-shock protein from the unicellular alga, Chlamydomonas reinhardtii, is described and a noted similarity of a 5'-upstream sequence motif to the G-box motif conserved in higher plants is found.
Journal ArticleDOI
Atmospheric input of nitrogen into the North Sea: ANICE project overview
Gerrit de Leeuw,Leo H. Cohen,Lise M. Frohn,G.L. Geernaert,Ole Hertel,Bjarne Jensen,Tim Jickells,Laura Klein,Gerard J. Kunz,S. Lund,Marcel M. Moerman,Frank Müller,B. Pedersen,Knut von Salzen,Knut von Salzen,K. Heinke Schlünzen,Michael Schulz,Carsten Ambelas Skjøth,Lise Lotte Sørensen,L. Spokes,Susanne Tamm,Elisabetta Vignati +21 more
TL;DR: In this paper, experimental and modelling work is conducted which aims to improve understanding of the processes involved in the chemical transformation, transport and deposition of atmospheric nitrogen compounds, including the influence of coastal zone processes.