Frank R. DeLeo

TL;DR: It is demonstrated that there has been recent clonal expansion and diversification of a subset of isolates classified as USA300, adding an evolutionary dimension to the epidemiology and emergence of USA300 and suggesting a similar mechanism for the pandemic occurrence and spread of penicillin-resistant S. aureus in the 1950s.

TL;DR: Recent progresses in understanding KPC-producing K. pneumoniae that are contributing to the authors' knowledge of plasmid and genome composition and structure among the KPC epidemic clone are discussed, and possible factors that influence its epidemiological success are identified.

TL;DR: PMN apoptosis is reviewed and the ability of microorganisms to alter this important process is reviewed to cause disease.

TL;DR: Progress made toward understanding the acquisition of antibiotic resistance in S. aureus is reviewed, with an emphasis on the molecular mechanisms underlying vancomycin resistance.

TL;DR: It is hypothesize that there are two fundamental outcomes for the interaction of bacterial pathogens with neutrophils: (i) phagocytosis of bacteria induces an apoptosis differentiation program in human PMNs that contributes to resolution of bacterial infection, or (ii)PhagocyTosis of microorganisms such as Str. pyogenes alters the apoptosis differentiate program in neutrophil, resulting in pathogen survival and disease.