抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1（PfPMP1）与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用，在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员，通过启动转录不同的var基因变异体为抗原变异提供了分子基础。

疟原虫var基因转换速率变化导致抗原变异[英]／Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A

The Hamiltonian H specifies the energy levels and time evolution of a quantum theory. A standard axiom of quantum mechanics requires that H be Hermitian because Hermiticity guarantees that the energy spectrum is real and that time evolution is unitary (probability-preserving). This paper describes an alternative formulation of quantum mechanics in which the mathematical axiom of Hermiticity (transpose +complex conjugate) is replaced by the physically transparent condition of space?time reflection ( ) symmetry. If H has an unbroken symmetry, then the spectrum is real. Examples of -symmetric non-Hermitian quantum-mechanical Hamiltonians are and . Amazingly, the energy levels of these Hamiltonians are all real and positive!Does a -symmetric Hamiltonian H specify a physical quantum theory in which the norms of states are positive and time evolution is unitary? The answer is that if H has an unbroken symmetry, then it has another symmetry represented by a linear operator . In terms of , one can construct a time-independent inner product with a positive-definite norm. Thus, -symmetric Hamiltonians describe a new class of complex quantum theories having positive probabilities and unitary time evolution.The Lee model provides an excellent example of a -symmetric Hamiltonian. The renormalized Lee-model Hamiltonian has a negative-norm 'ghost' state because renormalization causes the Hamiltonian to become non-Hermitian. For the past 50 years there have been many attempts to find a physical interpretation for the ghost, but all such attempts failed. The correct interpretation of the ghost is simply that the non-Hermitian Lee-model Hamiltonian is -symmetric. The operator for the Lee model is calculated exactly and in closed form and the ghost is shown to be a physical state having a positive norm. The ideas of symmetry are illustrated by using many quantum-mechanical and quantum-field-theoretic models.

https://iopscience.iop.org/article/10.1088/0034-4885/70/6/R03/pdf

Making sense of non-Hermitian Hamiltonians

Intermolecular And Surface Forces

Advanced Mathematical Methods for Scientists and Engineers

Magnetic fields influence many natural and man-made flows. They are routinely used in industry to heat, pump, stir and levitate liquid metals. There is the terrestrial magnetic field which is maintained by fluid motion in the earth's core, the solar magnetic field, which generates sunspots and solar flares, and the galactic field which influences the formation of stars. This is an introductory text on magnetohydrodynamics (MHD) - the study of the interaction of magnetic fields and conducting fluids. This book is intended to serve as an introductory text for advanced undergraduates and postgraduate students in physics, applied mathematics and engineering. The material in the text is heavily weighted towards incompressible flows and to terrestrial (as distinct from astrophysical) applications. The final sections of the text also contain an outline of the latest advances in the metallurgical applications of MHD and so are relevant to professional researchers in applied mathematics, engineering and metallurgy.

An Introduction to Magnetohydrodynamics

In a closed volume of molten sodium an intense single-vortex-like helical flow has been produced by an outside powered propeller At a flow rate of $067{\mathrm{m}}^{3}/\mathrm{s}$ a slowly growing magnetic field eigenmode was detected For a slightly lower flow, additional measurements showed a slow decay of this mode The measured results correspond satisfactorily with numerical predictions for the growth rates and frequencies

https://arxiv.org/pdf/physics/9912026.pdf

Detection of a flow induced magnetic field eigenmode in the riga dynamo facility

After the dynamo experiment in November 1999 [A. Gailitis et al., Phys. Rev. Lett. 84, 4365 (2000)] had shown magnetic field self-excitation in a spiraling liquid metal flow, in a second series of experiments emphasis was placed on the magnetic field saturation regime as the next principal step in the dynamo process. The dependence of the strength of the magnetic field on the rotation rate is studied. Various features of the saturated magnetic field are outlined and possible saturation mechanisms are discussed.

Magnetic Field Saturation in the Riga Dynamo Experiment

A recent Letter [R. Hollerbach and G. R\"udiger, Phys. Rev. Lett. 95, 124501 (2005)] has shown that the threshold for the onset of the magnetorotational instability in a Taylor-Couette flow is dramatically reduced if both axial and azimuthal magnetic fields are imposed. In agreement with this prediction, we present results of a Taylor-Couette experiment with the liquid metal alloy GaInSn, showing evidence for the existence of the magnetorotational instability at Reynolds numbers of order 1000 and Hartmann numbers of order 10.

Experimental evidence for magnetorotational instability in a Taylor-Couette flow under the influence of a helical magnetic field.

In the current-driven, kink-type Tayler instability (TI) a sufficiently strong azimuthal magnetic field becomes unstable against nonaxisymmetric perturbations. The TI has been discussed as a possible ingredient of the solar dynamo mechanism and a source of the helical structures in cosmic jets. It is also considered as a size-limiting factor for liquid metal batteries. We report on a liquid metal TI experiment using a cylindrical column of the eutectic alloy GaInSn to which electrical currents of up to 8 kA are applied. We present results of external magnetic field measurements that indicate the transient occurrence of the TI in good agreement with numerical predictions. The interference of TI with the competing large-scale convection, resulting from Joule heating, is also discussed.

Experimental evidence for a transient Tayler instability in a cylindrical liquid-metal column.

Cosmic magnetic fields, including the fields of planets, stars, and galaxies, are believed to be caused by dynamo action in moving electrically conducting fluids. While the theory and numerics of hydromagnetic dynamos have flourished during recent decades, an experimental validation of the effect was missing until recently. We sketch the long history towards a working laboratory dynamo. We report on the first successful experiments at the sodium facilities in Riga and Karlsruhe, and on other experiments which are carried out or planned at various places in the world.

/pdf/colloquium-laboratory-experiments-on-hydromagnetic-dynamos-1x1q36fbi1.pdf

Frank Stefani

Papers

Detection of a flow induced magnetic field eigenmode in the riga dynamo facility

Magnetic Field Saturation in the Riga Dynamo Experiment

Experimental evidence for magnetorotational instability in a Taylor-Couette flow under the influence of a helical magnetic field.

Experimental evidence for a transient Tayler instability in a cylindrical liquid-metal column.

Colloquium: Laboratory experiments on hydromagnetic dynamos