F
Fred Kueffer
Researcher at Medtronic plc
Publications - 35
Citations - 1675
Fred Kueffer is an academic researcher from Medtronic plc. The author has contributed to research in topics: Heart failure & Catheter ablation. The author has an hindex of 14, co-authored 31 publications receiving 1275 citations. Previous affiliations of Fred Kueffer include Brigham and Women's Hospital.
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Journal ArticleDOI
Transition from chronic compensated to acute decompensated heart failure: pathophysiological insights obtained from continuous monitoring of intracardiac pressures.
Michael R. Zile,Tom D. Bennett,Martin St. John Sutton,Yong K. Cho,Philip B. Adamson,Mark F. Aaron,Juan M. Aranda,William T. Abraham,Frank W. Smart,Lynne W. Stevenson,Fred Kueffer,Robert C. Bourge +11 more
TL;DR: Significant structural and functional differences were found between patients with SHF and those with DHF; however, elevated diastolic pressures play a pivotal role in the underlying pathophysiology of chronic compensated and acute decompensated HF in both SHf and DHF.
Journal ArticleDOI
Cryoballoon or radiofrequency ablation for symptomatic paroxysmal atrial fibrillation: Reintervention, rehospitalization, and quality-of-life outcomes in the FIRE and ICE trial
Karl-Heinz Kuck,Alexander Fürnkranz,K.R. Julian Chun,Andreas Metzner,Feifan Ouyang,Michael Schlüter,Arif Elvan,Hae W. Lim,Fred Kueffer,Thomas Arentz,Jean Paul Albenque,Claudio Tondo,Michael Kühne,Christian Sticherling,Josep Brugada +14 more
TL;DR: Patients treated with cryoballoon as opposed to RFC ablation had significantly fewer repeat ablations, direct-current cardioversions, all-cause re Hospitalizations, and cardiovascular rehospitalizations during follow-up and both patient groups improved in quality-of-life scores after AF ablation.
Journal ArticleDOI
Chronic Ambulatory Intracardiac Pressures and Future Heart Failure Events
Lynne W. Stevenson,Michael R. Zile,Tom D. Bennett,Fred Kueffer,Mariell Jessup,Philip B. Adamson,William T. Abraham,VenKatesh R. Manda,Robert C. Bourge +8 more
TL;DR: Despite current management, many patients with advanced HF live on a plateau of high filling pressures from which later events occur, and this risk is progressively higher with higher chronic ambulatory pressures.
Journal ArticleDOI
Repeat Ablation for Atrial Fibrillation Recurrence Post Cryoballoon or Radiofrequency Ablation in the FIRE and ICE Trial
Karl-Heinz Kuck,Jean Paul Albenque,K.R. Julian Chun,Alexander Fürnkranz,Mathias Busch,Arif Elvan,Michael Schlüter,Kendra M. Braegelmann,Fred Kueffer,Lauren Hemingway,Thomas Arentz,Claudio Tondo,Josep Brugada +12 more
TL;DR: Patients originally treated with the cryoballoon had significantly fewer reconnected PVs, which may reflect RFC catheter instability in certain left atrial regions, and thus required fewer lesions for reablation success, which resulted in similar acute success, duration of hospitalization, and antiarrhythmic drug prescription between the study cohorts.
Journal ArticleDOI
Determining the Feasibility of Spinal Cord Neuromodulation for the Treatment of Chronic Systolic Heart Failure: The DEFEAT-HF Study
Douglas P. Zipes,Petr Neuzil,Heinz Theres,David Caraway,Douglas L. Mann,Clas Mannheimer,Peter Van Buren,Cecilia Linde,Bengt Linderoth,Fred Kueffer,Scott A. Sarazin,Mike J. L. DeJongste,Defeat-Hf Trial Investigators +12 more
TL;DR: The present study does not provide evidence to support a meaningful change in clinical outcomes for HF patients receiving SCS, and the primary objective of the study was to evaluate the reduction in LVESVi after 6 months of SCS therapy in the treatment arm compared to the control arm.