F
Frederick Klauschen
Researcher at Humboldt University of Berlin
Publications - 238
Citations - 17312
Frederick Klauschen is an academic researcher from Humboldt University of Berlin. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 45, co-authored 170 publications receiving 12451 citations. Previous affiliations of Frederick Klauschen include Charité & National Institutes of Health.
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Journal ArticleDOI
Cancer of unknown primary (CUP) through the lens of precision oncology: a single institution perspective.
L. Weiss,Kathrin Heinrich,D Zhang,Klara Dorman,Katharina Rühlmann,Korbinian J. Q. Hasselmann,Frederick Klauschen,Jörg Kumbrink,Andreas Jung,Martina Rudelius,Steffen Ormanns,Wolfgang G. Kunz,Daniel Roessler,GP Beyer,Stefanie Corradini,Lucie Heinzerling,Michael R. Haas,Michael von Bergwelt-Baildon,Stefan Boeck,Volker Heinemann,C. Benedikt Westphalen +20 more
TL;DR: In this paper , the authors highlight the use of a molecular tumor board (MTB) in the therapeutic management of CUP patients and highlight the need for early implementation of comprehensive genomic profiling (CGP) into the management of cancer patients.
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Olfactomedin 4 associates with expression of differentiation markers but not with properties of cancer stemness, EMT nor metastatic spread in colorectal cancer
Stefanie Jaitner,Elise Pretzsch,Jens Neumann,A.J. Schäffauer,Matthias Schiemann,Martin K. Angele,Jörg Kumbrink,Sarah Schwitalla,Florian R. Greten,Lydia Brandl,Frederick Klauschen,David Horst,Thomas Kirchner,Andreas Jung +13 more
TL;DR: In this article , the authors used a combined approach of functional assays using forced OLFM4 overexpression in human colorectal cancer cell lines, xenograft mice, and an immunohistochemical approach using patient tissues to investigate the impact of Olfactomedin 4 on stemness, canonical Wnt signaling, properties of metastasis and differentiation as well as prognosis.
Journal ArticleDOI
Correction to "Integration of Metabolomics and Expression of Glycerol-3-phosphate Acyltransferase (GPAM) in Breast Cancer─Link to Patient Survival, Hormone Receptor Status, and Metabolic Profiling".
Scarlet F. Brockmöller,Elmar Bucher,Berit Maria Müller,Jan Budczies,Mika Hilvo,Julian L. Griffin,Matej Orešič,Olli Kallioniemi,Kristiina Iljin,Sibylle Loibl,Silvia Darb-Esfahani,Bruno Valentin Sinn,Frederick Klauschen,Judith Prinzler,Nikola Bangemann,Fakher Ismaeel,Oliver Fiehn,Manfred Dietel,Carsten Denkert +18 more
TL;DR: The Altmetric Attention Score as discussed by the authors is a quantitative measure of the attention that a research article has received online, and it is calculated using the Alt-Metric Attention Index (AUI) metric.
High-throughput cancer proteomic characterization using data-independent mass spectrometry (DIA-MS)
Chih Hsuan Yeh,Sebastian P Perner,Yanlong Ji,Thomas Oellerich,Kuan-Ting Pan,Corinna Friedrich,Simon Schallenberg,Marieluise Kirchner,Matthias Ziehm,Sylvia Niquet,Mohamed Hassan Haji,Christin Beier,Jens Neudecker,Frederick Klauschen,Philipp Mertins +14 more
TL;DR: In this article , a data-independent acquisition mass spectrometer (DIA-MS) was proposed to enhance proteome coverage and overall throughput for the purpose of proteome proteomics.
Journal ArticleDOI
PO-1824 Regression and deep learning for transcriptome-based HPV-status prediction in head and neck cancer
Kristian Unger,Elia Lombardo,Julia Hess,Christopher Kurz,Marco Riboldi,Sebastian Marschner,Philipp Baumeister,Kirsten Lauber,Ulrike Pflugradt,Axel Walch,Miguel Canis,Frederick Klauschen,Horst Zitzelsberger,Claus Belka,Guillaume Landry +14 more