F
Frederick Klauschen
Researcher at Humboldt University of Berlin
Publications - 238
Citations - 17312
Frederick Klauschen is an academic researcher from Humboldt University of Berlin. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 45, co-authored 170 publications receiving 12451 citations. Previous affiliations of Frederick Klauschen include Charité & National Institutes of Health.
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Journal ArticleDOI
High-protein diet more effectively reduces hepatic fat than low-protein diet despite lower autophagy and FGF21 levels
Chenchen Xu,Mariya Markova,Nicole Seebeck,Anne Loft,Silke Hornemann,Thomas Gantert,Stefan Kabisch,Kathleen Herz,Jennifer Loske,Mario Ost,Verena Coleman,Frederick Klauschen,Frederick Klauschen,Anke Rosenthal,Volker Lange,Jürgen Machann,Susanne Klaus,Tilman Grune,Stephan Herzig,Olga Pivovarova-Ramich,Andreas Pfeiffer +20 more
TL;DR: The aim was to investigate whether low‐ (LP) or high‐protein (HP) diets are more effective in reducing liver fat and reversing NAFLD and which mechanisms are involved.
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New network topology approaches reveal differential correlation patterns in breast cancer
TL;DR: Two correlation network topology based algorithms are developed that identify differential correlation patterns by comparing the local or global topology of correlation networks and permit to detect different kinds of correlation changes at the same level of significance.
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KRAS mutations in codon 12 or 13 are associated with worse prognosis in pancreatic ductal adenocarcinoma
Bruno Valentin Sinn,Jana K. Striefler,Marc Rudl,Annika Lehmann,Marcus Bahra,Carsten Denkert,Marianne Sinn,Jens Stieler,Frederick Klauschen,Jan Budczies,Wilko Weichert,Albrecht Stenzinger,Carsten Kamphues,Manfred Dietel,Hanno Riess +14 more
TL;DR: The results support the crucial role of KRAS mutational status in pancreatic cancer biology and suggest that it may serve as a prognostic marker for targeted therapies.
Posted ContentDOI
Single-cell RNA sequencing reveals distinct tumor microenvironmental patterns in lung adenocarcinoma
Philip Bischoff,Alexandra Trinks,Benedikt Obermayer,Jan Patrick Pett,Annika Lehmann,Philipp Jurmeister,Philipp Jurmeister,Aron Elsner,Tomasz Dziodzio,Jens-Carsten Rückert,Jens Neudecker,Christine S. Falk,Dieter Beule,Christine Sers,Christine Sers,Markus Morkel,Markus Morkel,David Horst,David Horst,Nils Blüthgen,Frederick Klauschen,Frederick Klauschen +21 more
TL;DR: The results show that single-cell gene expression profiling allows to identify patient subgroups based on the tumor microenvironment beyond cancer cell-centric profiling.
Journal ArticleDOI
High nuclear poly-(ADP-ribose)-polymerase expression is prognostic of improved survival in pancreatic cancer
Frederick Klauschen,Moritz von Winterfeld,Albrecht Stenzinger,Bruno Valentin Sinn,Jan Budczies,Carsten Kamphues,Marcus Bahra,Daniel Wittschieber,Wilco Weichert,Jana K. Striefler,Hanno Riess,Manfred Dietel,Carsten Denkert +12 more
TL;DR: Klauschen F, von Winterfeld M, Stenzinger A, Sinn B V, Budczies J, Kamphues C, Bahra M, Wittschieber D, Weichert W, Striefler J, Riess H, Dietel M & Denkert C Histopathology 61, 409–416.