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Frédérique Spyratos
Researcher at Curie Institute
Publications - 111
Citations - 5861
Frédérique Spyratos is an academic researcher from Curie Institute. The author has contributed to research in topics: Breast cancer & Population. The author has an hindex of 35, co-authored 111 publications receiving 5689 citations. Previous affiliations of Frédérique Spyratos include French Institute of Health and Medical Research.
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Journal ArticleDOI
Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients.
Maxime P. Look,Wim L. J. van Putten,Michael J. Duffy,Nadia Harbeck,Ib Jarle Christensen,Christoph Thomssen,Ronald E. Kates,Frédérique Spyratos,Mårten Fernö,Serenella Eppenberger-Castori,C. G. J. Fred Sweep,Kurt Ulm,J. P. Peyrat,Pierre-Marie Martin,Henri Magdelenat,Nils Brünner,Catherine Duggan,Björn W. Lisboa,Pär-Ola Bendahl,Véronique Quillien,A Daver,Gabriel Ricolleau,Marion E. Meijer-van Gelder,Peggy Manders,W. Edward Fiets,Marinus A. Blankenstein,Philippe Broët,Sylvie Romain,Günter Daxenbichler,Gudrun Windbichler,Tanja Cufer,Simona Borštnar,Willy Kueng,Louk V.A.M. Beex,Jan G. M. Klijn,Niall O'Higgins,Urs Eppenberger,Fritz Jänicke,Manfred Schmitt,John A. Foekens +39 more
TL;DR: For patients with lymph node-negative breast cancer, uPA and PAI-1 measurements in primary tumors may be especially useful for designing individualized treatment strategies.
Journal Article
The Lancet: saturday 11 November 1989
Frédérique Spyratos,Jean-Paul Brouillet,Annick Defrenne,Kamel Hacène,Jacques Rouëssé,Thierry Maudelonde,M. Brunet,Catherine Andrieu,Andree Desplaces,Henri Rochefort +9 more
Journal ArticleDOI
Genetic alteration of the c-myc protooncogene (MYC) in human primary breast carcinomas.
Chantal Escot,Charles Theillet,Rosette Lidereau,Frédérique Spyratos,Marie-Hélène Champème,Jean Gest,Robert Callahan +6 more
TL;DR: The frequency with which the c-myc gene is altered and its correlation with age suggest that it may play a role in the development of breast carcinomas.
Journal ArticleDOI
Prognostic value of histologic grade nuclear components of Scarff-Bloom-Richardson (SBR): an improved score modification based on a multivariate analysis of 1262 invasive ductal breast carcinomas
TL;DR: The modified SBR (MSBR), defined five new risk subgroups with statistically different risk ratios for MFS, and was the most important factor for prediction of relapse of MFS (P < 0.00001).
Journal ArticleDOI
Cathepsin D: an independent prognostic factor for metastasis of breast cancer.
Frédérique Spyratos,Kamel Hacène,Jacques Rouëssé,M. Brunet,Catherine Andrieu,Andree Desplaces,Jean-Paul Brouillet,Annick Defrenne,Thierry Maudelonde,Henri Rochefort +9 more
TL;DR: Cathepsin D assay may prove particularly useful in identifying women who, though without lymph node involvement at presentation, are at high risk of metastatic disease.