Showing papers by "Fumihiko Matsuda published in 1987"
TL;DR: Six variable-region (V) gene segments of the human immunoglobulin heavy-chain (H) segments were isolated and sequenced using the V71-2 segment as probe, creating a new family that is homologous to the mouse Vh36-60 family.
161 citations
TL;DR: Since the recombinant factors were also shown to affect bone marrow‐derived cells other than B cells, the names of interleukins 4 and 5 were proposed for IgG1 induction factor and T cell replacing factor, respectively.
Abstract: We have cloned cDNAs for IgG, induction factor and T cell replacing factor. The recombinant factors were shown to have multiple activities on B cells, which could explain most, if not all, of B cell growth and differentiation factor activities so far claimed. Since the recombinant factors were also shown to affect bone marrow-derived cells other than B cells, the names of interleukins 4 and 5 were proposed for IgG1 induction factor and T cell replacing factor, respectively.